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蛆虫清创治疗在糖尿病足溃疡中的作用
引用本文:王爱萍,蒋克春,王伟,柳岚,陈寅晨. 蛆虫清创治疗在糖尿病足溃疡中的作用[J]. 国际内分泌代谢杂志, 2011, 31(4): 243-245. DOI: 10.3760/cma.j.issn.1673-4157.2011.04.008
作者姓名:王爱萍  蒋克春  王伟  柳岚  陈寅晨
作者单位:解放军第454医院内分泌科,南京,210002
摘    要:
糖尿病足是糖尿病并发症之一.丝光绿蝇的幼虫具有独特的生物学特性,只吃腐烂组织、对活体组织无影响,且能分泌蛋白水解酶,降解、液化伤口的坏死组织.蛆虫清创治疗(maggotdebridement therapy,MDT)有500多年的历史,但直到1983年才重新在欧洲恢复使用,2004年获美国食品药品监督管理局(FDA)正...

关 键 词:蛆虫  糖尿病    溃疡

Role of maggot debridement therapy in diabetic foot ulcers
WANG Ai-ping,JIANG Ke-chun,WANG Wei,LIU Lan,CHEN Yin-chen. Role of maggot debridement therapy in diabetic foot ulcers[J]. International JOurnal of Endocrinology and Metabolism, 2011, 31(4): 243-245. DOI: 10.3760/cma.j.issn.1673-4157.2011.04.008
Authors:WANG Ai-ping  JIANG Ke-chun  WANG Wei  LIU Lan  CHEN Yin-chen
Abstract:
Diabetic foot is one of the diabetic complications. Lucilia sericata has unique biological properties,eating rotten tissue and none of living tissue, secreting proteolytic enzyme which can degrade and liquify necrotic tissue. Maggot debridement therapy (MDT) has a 500-year history,and to regain attention in Europe till 1983 ,and not be admitted by FDA until 2004. The effect of MDT on diabetic foot ulcers(DFUs) includes three aspects by various mechanism,which are cleaning up the wounds, promoting growth and resisting bacteria. MDT can be used to treat many types of wound,but should not be applied to wounds that have a tendency to bleed easily,or that communicate with a body cavity or internal organ, and that near to any large blood vessels.
Keywords:Maggot  Diabetes mellitus  Foot  Ulcer
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