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| 细胞因子风暴与肝衰竭 | |
| 引用本文： | 陈智,朱海红,杨英. 细胞因子风暴与肝衰竭[J]. 临床肝胆病杂志, 2014, 0(10): 981-983 |
| 作者姓名： | 陈智 朱海红 杨英 |
| 作者单位： | 浙江大学医学院附属第一医院 传染病诊治国家重点实验室,杭州,310003 |
| 基金项目： | 国家科技部“十二五”重大专项 |
| 摘 要： | 细胞因子风暴(cytokine storm)在肝衰竭发病机制中起十分重要的作用,与肝衰竭过程中的肝细胞坏死和疾病临床预后密切相关。介绍了以Kupffer细胞为线索,肝衰竭发生、发展过程中各相关细胞及细胞因子相互影响、共同作用,导致肝组织严重损伤和坏死的机制。指出细胞因子的研究,将有助于肝衰竭早期诊断、病情分析和个体化治疗水平的提高。 |
| 关 键 词： | 肝功能衰竭 细胞因子 枯否细胞 |
Cytokine storm and liver failure |
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| CHEN Zhi,ZHU Haihong,YANG Ying. Cytokine storm and liver failure[J]. Chinese Journal of Clinical Hepatology, 2014, 0(10): 981-983 | |
| Authors: | CHEN Zhi ZHU Haihong YANG Ying |
| Affiliation: | ( State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospi- tal, School of Medicine, Zhejiang University, Hangzhou 310003, China) |
| Abstract: | Cytokine storm plays an important role in the pathogenesis of liver failure.It is closely related to hepatocyte necrosis in the clini-cal course and the prognosis of this disease.With Kupffer cells as a clue,it is elucidated that related cells and cytokines influence each other and jointly function in the development and progression of liver failure,leading to serious liver tissue damage and necrosis.Cytokine -based research can help improve early diagnosis,disease assessment,and individualized treatment for liver failure. |
| Keywords: | liver failure cytokine kupffer cells |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |