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| 系统性红斑狼疮并发肺动脉高压37例临床分析 | |
| 引用本文： | 刘占诺,慈春增,王晓东,齐欣泰. 系统性红斑狼疮并发肺动脉高压37例临床分析[J]. 现代医药卫生, 2011, 27(22): 3378-3380 |
| 作者姓名： | 刘占诺 慈春增 王晓东 齐欣泰 |
| 作者单位： | 1. 潍坊医学院,山东潍坊,261053 2. 潍坊医学院附属医院,山东潍坊,261031 |
| 摘 要： | 目的:探讨系统性红斑狼疮(systemic lupus erythematosus,SLE)并肺动脉高压(pulmonary arterial hypertension,PAH)患者的临床特点及发病机制,方法:37例经彩色多普勒超声心动图诊断明确、资料完整的SLE合并PAH患者,对其临床症状、实验室指标、超声心动图特点、SLEDAI积分进行回顺性分析.结果:本组患者抗nRNP阳性、抗心磷脂抗体IgG异常、浆膜炎、SLEDAI评分和肺间质病变出现率均增高,与PAH的发生率成正相关结论:SLE是自身免疫性疾病中合并PAH较常见的疾病,对于出现雷诺现象、皮肤血管炎、抗nRNP阳性、抗心磷脂抗体IgG阳性以及浆膜炎和肺间质病变的SLE患者应警惕PAH的可能,彩色多普勒超声心动图及相关检查有利于早期诊断. |
| 关 键 词： | 肺动脉高压 系统性红斑狼疮 雷诺现象 皮肤血管炎 |
Clinical analysis of systemic lupus erythematosus complicating pulmonary hypertension in 37 cases |
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| LIU Zhan-nuo , CI Chun-zeng , WANG Xiao-dong , QI Xin-tai. Clinical analysis of systemic lupus erythematosus complicating pulmonary hypertension in 37 cases[J]. JOURNAL OF MODERN MEDICINE & HEALTH, 2011, 27(22): 3378-3380 | |
| Authors: | LIU Zhan-nuo CI Chun-zeng WANG Xiao-dong QI Xin-tai |
| Affiliation: | LIU Zhan-nuo1,CI Chun-zeng2,WANG Xiao-dong2,QI Xin-tai1(1.Weifang Medical College,Weifang,Shandong 261053,China,2.Affiliated Hospital,Weifang Medical College,Shandong 261031,China) |
| Abstract: | Objective:To study the clinical manifestations,mechanism,diagnosis and treatment of pulmonary arterial hypertention(PAH) in systemic lupus erytbamatosus(SLE).Methods:From January 2006 to June 2011,SLE patients without prior diagnosis were admitted in our hospital.Among them,37 cases were identified to have concomitant PAH defined by echocardiography.The clinical data of 37 cases were analyzed retrospectively.Results:The incidence of PAH was 10.7% in these SLE cases.Positive correlations were found between t... |
| Keywords: | Pulmonary hypertension Systemic lupus erythematosus Raynaud phenomenon |
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