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法莫替丁治疗消化性溃疡60例
引用本文:林庚金,张善身,曹克升. 法莫替丁治疗消化性溃疡60例[J]. 中国新药与临床杂志, 1992, 0(4)
作者姓名:林庚金  张善身  曹克升
作者单位:上海医科大学华山医院 上海200040(林庚金),上海医科大学中山医院 上海200032(张善身),上海华东医院 上海200040(曹克升)
摘    要:
60例(男50,女10,年龄43±8a)经内窥镜证实的活动性消化性溃疡患者,口服法莫替丁40mg,qn,疗程2-4wk或延至6-9wk。溃疡愈合率DU2,4,6 wk分别为50%,84%,92%,SU2,4,6,8 wk分别为40%,68%,73%,82%。服药后3,7,14 d上腹痛缓解率DU为50%,80%,100%,SU为40%,75%,95%。未见严重不良反应。故法莫替丁对溃疡病,尤其是DU是一有效和安全药物。

关 键 词:法莫替丁/治疗应用  消化性溃疡/药物疗法  促胃液素

Famotidine in the treatment of peptic ulcer in 60 patients
LIN Geng-Jin. Famotidine in the treatment of peptic ulcer in 60 patients[J]. Chinese Journal of New Drugs and Clinical Remedies, 1992, 0(4)
Authors:LIN Geng-Jin
Abstract:
Sixty patients (M 50, F 10, age 43 + 8 a) with active peptic ulcer confirmed by endoscopy were assigned to receive famotidine 40 mg qn for 2-4 wk or more. The healing rates were 50%, 84%, 92% at 2, 4, 6 wk respectively in duodenal ulcer (DU), and 40%, 68%, 73%, 82% at 2, 4, 6, 8 wk respectively in stom- ach ulcer(SU) after therapy. The epigastric pain relief rates were 50%, 80%, 100% in DU and 40%, 75%, 95% in SU after 3, 7, 14 d respectively. There were no serious adverse effects. We believe that famotidine is an effective and safe drug for the treatment of peptic ulcer especially for DU.
Keywords:famotidine/therapeutic use  peptic ulcer/drug therapy  gastrins
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