腹股沟疝修补术围手术期预防用抗菌药物专项整治效果

目的了解某院抗菌药物临床应用专项整治活动开展的效果。方法查阅专项整治活动开展前（2011年）和开展后（2012年）普通外科腹股沟疝修补术患者病历资料，评价其围手术期预防用抗菌药物的合理性并进行比较。结果2011年腹股沟疝修补术围手术期抗菌药物预防使用率为53.90%（76/141），2012年下降至5.59%（10/179），两组比较，差异有统计学意义（χ2=93.68，P＜0.05）；整治后（2012年）的人均抗菌药物费用为人民币81.52元，较整治前（2011年）的624.73元减少了543.21元，下降了86.95%；联合用药较少，均以单用一种抗菌药物为主，分别占93.42%和80.00%。两组患者均未发生手术部位感染。结论通过开展抗菌药物临床应用专项整治活动，有效降低了腹股沟疝修补术围手术期抗菌药物预防使用率及相关费用。

Effect of special rectification of perioperative antimicrobial prophylaxis in inguinal hernia repair

ObjectiveTo evaluate the effect of special rectification of clinical antimicrobial use in a hospital.MethodsMedical records of patients receiving inguinal hernia repair before (in 2011) and after (in 2012) the performance of special rectification  were reviewed, and the rationality of perioperative antimicrobial prophylaxis was compared. ResultsProphylactic antimicrobial usage rate in patients receiving  inguinal hernia repair decreased from 53.90%(76/114) in 2011 to 5.59%(10/179) in 2012, the difference was significant   (χ2=93.68，P＜0.05) ; average expense of antimicrobial use per patient decreased by  86.95% (from ￥ 624.73  in 2011 to ￥ 81.52  in 2012)；Combination use and single use was 93.42% and 80. 00% respectively.Surgical site infection did not occur in both groups. ConclusionThrough the special rectification activities of the clinical antimicrobial use, perioperative antimicrobial prophylaxis  and expense of antimicrobial agents in patients receiving inguinal hernia repair is effectively reduced.