Synthesis and alpha-adrenolytic activities of 2-(1,4-benzodioxan-2-yl- methyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives |
| |
| Authors: | E Glusa H Grüner A Hagen D Lohmann H Foken |
| |
| Affiliation: | Institut für Pharmakologie der Medizinischen Akademie Erfurt. |
| |
| Abstract: | ![]()
The synthesis of the title compounds starting from 2-Chlormethylbenzdioxan and Tetrahydroisochinolines is presented. Their actions on the platelet aggregation and the inhibition of alpha-adrenoceptors at the isolated rabbit aorta and the vas deferens of the guinea pig were investigated. |
| |
| Keywords: | |
|
|
