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周围型肺癌的CT征象与癌细胞DNA含量的关系
引用本文:姜慧杰,于丽娟,曲丽英,于树江. 周围型肺癌的CT征象与癌细胞DNA含量的关系[J]. 中国医学影像学杂志, 2002, 10(1): 36-37,40
作者姓名:姜慧杰  于丽娟  曲丽英  于树江
作者单位:1. 150086,哈尔滨市,哈尔滨医科大学附属第二医院CT室
2. 150040,哈尔滨市,哈尔滨医科大学附属第三医院放射线科
摘    要:
目的 :探讨周围型肺癌DNA含量及其与CT征象的关系。材料和方法 :用流式细胞分析术检测 5 0例有术前CT检查并经手术病理证实的周围型肺癌石蜡包埋标本的细胞核DNA含量。结果 :CT显示分叶征、毛刺征、棘突征 ,有纵隔、肺门淋巴结转移的有无 ,其DNA异倍体检出率均有统计学差异。结论 :周围型肺癌出现分叶征、毛刺征、棘突征且有纵隔、肺门淋巴结转移的CT征象与癌细胞核的DNA含量有显著关系。

关 键 词:周围型肺癌  CT  DNA  流式细胞术
修稿时间:2001-04-24

Study on the Correlation Between DNA Contents of Cell and CT Appearance in Peripheral Lung Carcinoma
Jiang Huijie,Yu Lijuan,Qu Liying,Yu Shujiang. Study on the Correlation Between DNA Contents of Cell and CT Appearance in Peripheral Lung Carcinoma[J]. Chinese Journal of Medical Imaging, 2002, 10(1): 36-37,40
Authors:Jiang Huijie  Yu Lijuan  Qu Liying  Yu Shujiang
Abstract:
Purpose:To evaluate the correlation between CT appearance and DNA contents in peripheral lung carcinoma. Marerials and methods: paraffin embedded specimens of 50 cases with peripheral lung carcinoma proved by CT,operation and pathology were examined,DNA contents of cell nucleus were determined by flow cytometry(FCM). Results:Aneuploidy had statistic difference in lung carcinoma with lobulation,spiculate margin,spiculate protuberance and mediastional lymph node matastasis.Conclusion:peripheral lung carcinoma with lobulation,speculated margin,spiculate protuberance and mediastional lymph node matastasis has significant correlation with DNA contents.
Keywords:peripheral lung carcinoma  CT  DNA  flow cytometry
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