Successful treatment of acute promyelocytic leukemia in a patient on hemodialysis |
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| Authors: | Yoshiki Tsuchiya Yoshifumi Ubara Tatsuya Suwabe Junichi Hoshino Keiichi Sumida Rikako Hiramatsu Eiko Hasegawa Masayuki Yamanouchi Noriko Hayami Yuji Marui Naoki Sawa Fumi Takemoto Kenmei Takaichi |
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| Affiliation: | Nephrology Center, Toranomon Hospital Kajigaya, 1-3-1 Kajigaya Takatsu, Kawasaki, Kanagawa 213-8587, Japan. yoshiki1209@gmail.com |
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| Abstract: | ![]()
Acute promyelocytic leukemia (APL) has the best prognosis among acute leukemias, but there is little data about APL in patients on hemodialysis. A 64-year-old hemodialysis patient was successfully treated for APL by induction therapy with all-trans retinoic acid (ATRA), three courses of consolidation therapy with Ara-C, mitomycin?C (MIT), daunorubicin (DNR), and idarubicin (IDR), and maintenance therapy with ATRA. Complete remission has been maintained for 42?months in this patient. With dose modification, ATRA and chemotherapy may be safely given to patients on hemodialysis. |
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