A new HLA-A allele, HLA-A*6824, identified in three unrelated individuals |
| |
Authors: | Davey S Carter V Goodman R Day S Brown C Morris J Key T Bendukidze N Dunn P P J |
| |
Affiliation: | H&I Laboratory, National Blood Service, Colindale, London, UK. |
| |
Abstract: | A novel allele, human leukocyte antigen (HLA)-A*6824, has been identified in three unrelated individuals of northwestern European origin in a period of less than 4 months, implying that this allele may be quite common in this population. HLA-A*6824 differs from A*680102 by a single nucleotide change at position 275 in exon 2, which results in a conservative amino acid substitution from lysine to arginine in the peptide-binding groove at codon 68. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|