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A new HLA-A allele, HLA-A*6824, identified in three unrelated individuals
Authors:Davey S  Carter V  Goodman R  Day S  Brown C  Morris J  Key T  Bendukidze N  Dunn P P J
Affiliation:H&I Laboratory, National Blood Service, Colindale, London, UK.
Abstract:
A novel allele, human leukocyte antigen (HLA)-A*6824, has been identified in three unrelated individuals of northwestern European origin in a period of less than 4 months, implying that this allele may be quite common in this population. HLA-A*6824 differs from A*680102 by a single nucleotide change at position 275 in exon 2, which results in a conservative amino acid substitution from lysine to arginine in the peptide-binding groove at codon 68.
Keywords:
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