Morphology of Ammon's horn of the rat hippocampus in tissue culture

The principles of morphogenesis of Ammon's horn of the neonatal rat hippocampus in tissue culture (area CA_1-2) were studied by light-optical and electron-microscopic methods. Analysis of 5-, 12-, and 21-day cultures revealed maturation of the hippocampal pyramidal cells in vitro, the development of a protein-synthesizing system, and synaptogenesis. The synchronous development of the synaptic structures, of the protein-synthesizing system of the cell, and of electrogenesis suggests that these are interconnected factors.Laboratory of Neurophysiological Mechanisms of Adaptation, Institute of Clinical and Experimental Medicine, Siberian Branch, Academy of medical Sciences of the USSR, Novosibirsk. (Presented by Academician of the Academy of Medical Sciences of the USSR V. P. Kaznacheev.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 84, No. 8, pp. 229–231, August, 1977.