| 吲哚拉新药物的多晶型研究——(1)多晶型的制备与鉴别 |
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| 引用本文： | 金光洙,王晶,沈莉,苏德森. 吲哚拉新药物的多晶型研究——(1)多晶型的制备与鉴别[J]. 沈阳药科大学学报, 1992, 0(3) |
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| 作者姓名： | 金光洙 王晶 沈莉 苏德森 |
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| 作者单位： | 沈阳药学院物理化学教研室，沈阳药学院物理化学教研室，沈阳药学院，沈阳药学院物理药学研究室 54期学生 |
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| 摘 要： | 本文分别选择乙醇、乙醇-水、丙酮、丙酮-水、甲醇、乙腈、丙酮-石油醚、苯、无水乙醚等溶剂,制备了吲哚拉新的多晶型,通过差热分析、红外吸收分光光度法及X射线粉末衍射法等鉴别,确定吲哚拉新药物结晶至少存在三种不同的晶型。
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| 关 键 词： | 吲哚拉新 多晶型 X射线粉末衍射 |
POLYMORPHISM OF INDOLACIN——(1) Preparation and Identification of Polymorphic Forms |
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| Jin Guangzhu Wang Jing Shen Li Dept. of Phy. Chem. Su Desen Res. Dept. of Phy. Pharm.. POLYMORPHISM OF INDOLACIN——(1) Preparation and Identification of Polymorphic Forms[J]. Journal of Shenyang Pharmaceutical University, 1992, 0(3) |
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| Authors: | Jin Guangzhu Wang Jing Shen Li Dept. of Phy. Chem. Su Desen Res. Dept. of Phy. Pharm. |
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| Affiliation: | Jin Guangzhu Wang Jing Shen Li Dept. of Phy. Chem. Su Desen Res. Dept. of Phy. Pharm. |
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| Abstract: | Polymorphic forms of indolacin were prepared by using such solvents as ethanol, ethanol-water, aceton, aceton-water, methanol, aceton-ether from petroleum, anhydrous acetonitrile, benzene and anhydrous ether. These resulting crystalline polymorphic forms when identified by differential scanning calorimetry, infrared spectrophotometry and X-ray powder diffraction were more than three in number. |
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| Keywords: | Indolacin Polymorphism X-ray powder diffraction |
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