冠状动脉介入术后患者情绪障碍调查研究

目的研究经皮冠状动脉介入治疗（PCI）术后患者焦虑、抑郁障碍的发生情况及其相关因素分析。方法选择2008年1月至2009年12月于北京安贞医院行PCI治疗的全部患者,采用17项汉密尔顿焦虑抑郁量表（HAMA,HAMD）于术后1 d内对其进行焦虑、抑郁障碍评分。HAMA≥14分定义为焦虑,HAMD≥17分定义为抑郁。结果 PCI术后入选的2 028例患者中,合并焦虑者为935例（46.10%）,合并抑郁者为732例（36.09%）,同时存在焦虑、抑郁者为482例（23.77%）。logistic多因素回归分析显示,女性、自费医疗是PCI术后发生焦虑的独立预测因素。而女性、既往合并抑郁病史、自费医疗是PCI术后发生抑郁的独立预测因素。结论 PCI术后有较高比例的患者存在焦虑和抑郁,因此有必要对PCI术后的患者进行干预治疗。

Anxiety and depression in patients undertaken percutaneous coronary intervention

Objective To investigate the anxiety and depression as well as the related risk factors of patients undertaken percutaneous coronary intervention（PCI）.Methods A total of 2 028 patients with PCI were investigated between January 2008 and December 2009.The tables of HAMA and HAMD were applied for the study one day after the procedure.Depression was defined as score of 17 or over by the table of HAMD,and anxiety as score of 14 or over by the table of HAMA.Results Nine hundred and thirty-five（46.1%） and 732（36.1%） patients with PCI had anxiety and depression respectively.Four hundred and eighty-two（28.7%）patients had the both symptoms.The variable of poor pecuniary condition,female,and post-procedure depression were associated with dysthymic disorder after adjusting for other factors that might affect anxiety and depression.Conclusion A high proportion of PCI patients have symptom of anxiety and depression.It is necessary to provide treatment for their dysthymic disorders.