脑微出血危险因素、可能发生机制及其并缺血性脑卒中的治疗进展

脑微出血(CMBs)是脑小血管病的重要影像学表现,常在缺血性脑卒中、颅内出血、痴呆等患者经颅MRI检查时被检出。近年来,随着医学影像学技术的进步,CMBs的检出率呈逐渐上升趋势。有研究发现,CMBs的存在会增加脑卒中发生率及恶化风险,对缺血性脑卒中的发生及病情进展具有一定的预测价值。因此,本文详细阐述了CMBs的流行病学、危险因素、可能发生机制、临床表现,并进一步总结CMBs与缺血性脑卒中的相关性及其并缺血性脑卒中的治疗方案,旨在为科研工作者更深入地研究CMBs提供思路,最终将研究成果运用于临床,进而指导CMBs并缺血性脑卒中患者的个体化防治。

Risk Factors,Possible Mechanism of Cerebral Microbleeds and Treatment Progress of Cerebral Microbleeds Complicated with Ischemic Stroke

Cerebral microbleeds(CMBs)is an important imaging manifestation of cerebral small vessel diseases,which is often detected by brain MRI examinations in patients with ischemic stroke,intracranial hemorrhage and dementia.In recent years,with the development of medical imaging technology,the detection rate of CMBs has been gradually increasing.Some studies have shown that the existence of CMBs will increase the risk of stroke occurrence and deterioration,which has a certain predictive value for the occurrence and progression of ischemic stroke.Therefore,this article elaborates on the epidemiology,risk factors,possible mechanisms,and clinical manifestations of CMBs,and further summarizes the correlation between CMBs and ischemic stroke and the treatment plan for CMBs complicated with ischemic stroke,aiming to provide research ideas for scientific researchers to study CMBs more deeply,and finally apply the research results to the clinic,and then guide the individualized prevention and treatment of patients with CMBs complicated with ischemic stroke.