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A method for in vivo high resolution MRI of rat spinal cord injury
Authors:John C. Ford  David B. Hackney  Peter M. Joseph  Megan Phelan  David C. Alsop  Stacy L. Tabor  Christopher M. Hand  Ronald S. Markowitz  Perry Black
Abstract:
We have developed an implanted radiofrequency coil to obtain high resolution in vivo MR images at 1.9 Tesla of rat spinal cords that have been injured using a standardized weight drop technique. The signal-to-noise ratio and motion artifact suppression of these images is superior to that achieved in earlier attempts at this field strength using an external surface coil. The high quality and spatial resolution provided by this technique afford the possibility for longitudinal studies of experimental spinal cord injury before and after treatment, as well as detailed correlation of in vivo MRI contrast, histopathological findings, and functional deficit, in a controlled setting.
Keywords:spinal cord injury  high resolution MRI  radiofrequency coils
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