| 奥曲肽治疗32例老年人中晚期肝癌临床疗效观察 |
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| 引用本文： | 杨美南,肖斌,王晓莲,薛绮萍. 奥曲肽治疗32例老年人中晚期肝癌临床疗效观察[J]. 实用临床医药杂志, 2003, 7(4): 302-304 |
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| 作者姓名： | 杨美南 肖斌 王晓莲 薛绮萍 |
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| 作者单位： | 南京医科大学第一附属医院老年医学科,江苏,南京,210029;南京医科大学第一附属医院老年医学科,江苏,南京,210029;南京医科大学第一附属医院老年医学科,江苏,南京,210029;南京医科大学第一附属医院老年医学科,江苏,南京,210029 |
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| 摘 要： | 目的 探讨奥曲肽治疗老年中晚期原发性肝癌的临床疗效和安全性。方法 采用随机、对照方法,将65例老年中晚期肝癌分为奥曲肽组32例,对照组33例。按WHO癌症治疗客观疗效评定。结果 2组近期疗效无显著差异,但治疗组中位生存期、6个月生存率分别为(11.61±3.50)月、61.54%,远高于对照组的(5.64±1.44)月、32%(P<0.05),且治疗组生存质量有明显改善。结论 奥曲肽能延长中晚期肝癌患者临床生存期,提高生活质量,副反应轻。
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| 关 键 词： | 奥曲肽 肝癌 生存质量 生长抑素类似物 |
| 文章编号： | 1672-2353(2003)04-0302-03 |
| 修稿时间： | 2003-06-25 |
EFFECTS OF OCTREOTIDE IN ELDERLY PATIENTS WITH ADVANCED PRIMARY HEPATIC CANCER |
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| YANG Mei-nan,XIAO Bin,WANG Xiao-lian,XUE Yi-ping. EFFECTS OF OCTREOTIDE IN ELDERLY PATIENTS WITH ADVANCED PRIMARY HEPATIC CANCER[J]. Journal of Clinical Medicine in Practice, 2003, 7(4): 302-304 |
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| Authors: | YANG Mei-nan XIAO Bin WANG Xiao-lian XUE Yi-ping |
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| Abstract: | Objective: To evaluate the effects and safety of administration of octreotide in elderly patients with advanced primary hepatic cancer (PHC). Methods: Sixty-five PHCs were divided randomly into two groups: octreotide group(n=32) and control group(n=33). The effects of treatment were assessed with the WHO criteria (CR,PR,NC,PD).Results:5 PHCs of octreotide group were PR while no CR or PR observed in control group(P<0.05). Side effects were observed in 3 PHCs of octreotide group (3/32) while none in control group.Conclusion: Octreotide treatment is beneficial on prognosis of advanced PHC in elderly patients and with light side effects. |
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| Keywords: | octreotide hepatic cancer quality of life somatostain analogue |
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