| 乙型肝炎治疗性疫苗研究进展 |
| |
| 引用本文： | 杨富强,饶桂荣.乙型肝炎治疗性疫苗研究进展[J].传染病信息,2015,28(2):65-69. |
| |
| 作者姓名： | 杨富强 饶桂荣 |
| |
| 作者单位： | 解放军第四五八医院全军肝病中心, 广州,510600 |
| |
| 基金项目： | 国家"十二五"科技重大专项，2014年广东省自然科学基金 |
| |
| 摘 要： | 当前国内外已经研发了一系列慢性乙型肝炎(chronic hepatitis B, CHB)治疗性疫苗,主要有蛋白类疫苗、T细胞表位肽疫苗、DNA疫苗和细胞类(树突状细胞等)疫苗等. 本文对国内外相关乙型肝炎治疗性疫苗的研究进展进行综述,对存在问题进行讨论分析,并提出解决方案,以期为治疗CHB的临床研究提供参考.
|
| 关 键 词： | 疫苗 乙型肝炎 慢性 免疫系统过程 |
Research progress of therapeutic vaccines against hepatitis B |
| |
| YANG Fu-qiang,RAO Gui-rong.Research progress of therapeutic vaccines against hepatitis B[J].Infectious Disease Information,2015,28(2):65-69. |
| |
| Authors: | YANG Fu-qiang RAO Gui-rong |
| |
| Institution: | YANG Fu-qiang;RAO Gui-rong;Liver Disease Research Center, 458 Hospital of PLA; |
| |
| Abstract: | A series of therapeutic vaccines against chronic hepatitis B (CHB), including the ones of HBV protein, the specific epitope peptide, DNA plasmids and cells (dendritic cells), have been studied and developed. The authors present a literature review on the research progress of therapeutic vaccines against hepatitis B and propose a solution for the obstacles we are facing during the de-velopment of therapeutic vaccines, so as to provide a reference for clinical research for management of CHB. |
| |
| Keywords: | vaccines hepatitis B chronic immune system processes |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
