直肠癌Miles术后会阴部伤口愈合缓慢的影响因素分析

目的:探讨直肠癌Miles术后会阴部伤口愈合缓慢的影响因素.方法:回顾性分析210例经病理诊断明确且行Miles术的直肠癌患者临床资料,分析可能影响Miles术后切口愈合不良的因素,包括:性别、年龄、术前营养状态、术中盆腔腹膜修复与否、术前放疗以及术前、术后是否行高压氧治疗等.结果:直肠癌Miles术后切口Ⅰ期愈合率在性别、年龄、术前营养状态以及术中盆腔腹膜修复与否间差异均无统计学意义(P>0.05),患者术前放疗切口Ⅰ期愈合率明显低于术前未行放疗者(P<0.01),而患者术前以及术后行高压氧疗切口Ⅰ期愈合率高于术前及术后未行高压氧疗者(P<0.05).结论:术前放疗能延缓直肠癌Miles术后切口Ⅰ期愈合,而术前及术后高压氧疗能促进直肠癌Miles术后切口Ⅰ期愈合.高压氧疗可用于临床预防直肠癌Miles术后切口愈合不良.

The influencing factor analysis of the slow healing of perineal wound after Miles operation of rectal cancer

Objective:To investigate the influencing factors of the slow healing of perineal wound after Miles operation of rectal cancer. Methods:The clinical data of 210 rectal cancer patients diagnosed by pathology were retrospectively analyzed after Miles operation. The influencing factors of the slow healing of perineal wound,which included the gender,age,preoperative nutritional status, intraoperative pelvic peritoneal repair or not, preoperative radiotherapy or not and preoperative and postoperative hyperbaric oxygen therapy,were investigated,and the correlation of the poor healing of incision with influencing factor were statistically analyzed. Results:The difference of the primary healing rate of incision in patients with different gender,age,preoperative nutritional status and peritoneal repair were not statistically significant(P>0. 05). The difference of the primary healing rate of incision in patients with preoperative radiotherapy was significant lower than that in patients without preoperative radiotherapy(P<0. 01),and the difference of the primary healing rate of incision in patients with preoperative and postoperative hyperbaric oxygen therapy was significant higher than that in patients without preoperative and postoperative hyperbaric oxygen therapy(P<0. 05). Conclusions:Conclusions:After Miles operation of rectal cancer,the preoperative radiotherapy can delay the primary healing of incision,the preoperative and postoperative hyperbaric oxygen therapy can promote the primary healing of incision,and the hyperbaric oxygen therapy can be used to prevent the poor wound healing.