| 大鼠脑出血后脑水肿模型的建立及评价 |
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| 引用本文： | 宫晔,陈衔城. 大鼠脑出血后脑水肿模型的建立及评价[J]. 中国临床神经科学, 1999, 7(3): 140-142 |
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| 作者姓名： | 宫晔 陈衔城 |
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| 作者单位： | 上海医科大学附属华山医院神经外科 200040(宫晔)，上海市华东医院 研究生(陈衔城)，上海市华东医院 导师(鲍伟民) |
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| 基金项目： | 上海医学发展基金首批重点研究课题(课题号9S20002) |
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| 摘 要： | 目的:研究血液凝血过程对自发性脑出血脑水肿的影响。方法与结果:我们参照Bullock和Yang方法制作成功大鼠自体定量新鲜无肝素未凝动脉血脑出血模型,并予改进,该模型成功率达80%,稳定性强,容易操作,大鼠全身反应小,便于观察。结论:是一种较理想的研究实验性脑出血后脑水肿的模型。
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| 关 键 词： | 脑出血 脑水肿 大鼠 动物模型 |
A Model of Brain Edema Following Intracerebral Hemorrhage in Rats |
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| Gong Ye,Chen Xian-Cheng,Bao Wei-Min. A Model of Brain Edema Following Intracerebral Hemorrhage in Rats[J]. Chinese Journal of Clinical Neurosciences, 1999, 7(3): 140-142 |
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| Authors: | Gong Ye Chen Xian-Cheng Bao Wei-Min |
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| Affiliation: | Gong Ye,Chen Xian-Cheng,Bao Wei-MinDepartment of Neurosurgery,Huashan Hospital of Shanghai Medical University,Shanghai,200040 |
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| Abstract: | Aim: To study a model of brain edema following intracerebral hemorrhage in rats. Methods & Results: The model is designed for investigating the role of the coagulation cascade in brain edema formation caused by intracerebral blood. Conclusion: The model minics the natural event that occurs with spontaneous intracerebral hemorrhage in humans and has more features. |
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| Keywords: | intracerebral hemorrhage brain edema rat animal model |
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