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The renal lesions of electrolyte imbalance. II. The combined effect on renal architecture of phosphate loading and potassium depletion
Authors:HOLLIDAY M A  WINTERS R W  WELT L G  MACDOWELL M  OLIVER J
Affiliation:From the Department of Pediatrics, Indiana University Medical Center, Department of Pediatrics and Department of Medicine, University of North Carolina, and the Renal Research Unit, Research Department, CIBA Pharmaceutical Products Inc., Summit, New Jersey
Abstract:Potassium depletion in rats augments the specific renal lesions of phosphate loading. Since it has been shown that phosphate loading increases the specific cardiac lesions of potassium deficiency (12), it is concluded that the similar types of electrolyte imbalance (potassium depletion-phosphate load) act conversely in the two organs.
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