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苯巴比妥负荷量分次给药治疗新生儿缺氧缺血性脑病71例疗效观察
引用本文:陈丽珠,陈永传,盛丽萍,陈永倖. 苯巴比妥负荷量分次给药治疗新生儿缺氧缺血性脑病71例疗效观察[J]. 海南医学, 2011, 22(8): 89-90
作者姓名:陈丽珠  陈永传  盛丽萍  陈永倖
作者单位:1. 海南省第二人民医院儿科,海南,五指山,572200
2. 北京和睦家医院检验科,北京,100016
3. 海南省人民医院呼吸内科,海南,海口,570311
摘    要:
目的 观察苯巴比妥负荷量分次给药治疗新生儿缺氧缺血性脑病(NHIE)的疗效.方法 回顾性总结了71例NHIE的临床资料,所有患儿均采用分次给予苯巴比妥负荷量(20mg·kg-1·d-1半量)进行治疗.结果 71例患儿中69例(97.2%)得到较好的治疗效果,2例分别因合并中度硬肿及肺出血,呼吸衰竭死亡.结论 苯巴比妥负...

关 键 词:苯巴比妥  新生儿缺氧缺血性脑病  疗效

Efficacy of phenobarbital semi-dose loading in treatment of neonatal hypoxic ischemic encephalopathy
CHEN Li-zhu,CHEN Yong-. Efficacy of phenobarbital semi-dose loading in treatment of neonatal hypoxic ischemic encephalopathy[J]. Hainan Medical Journal, 2011, 22(8): 89-90
Authors:CHEN Li-zhu  CHEN Yong-
Affiliation:chuan,SHENG Li-ping,et al.Department of Children Medicine of the Second People’s Hospital of Hainan Province,Wuzhishan 572200,Hainan,CHINA
Abstract:
Objective To observe the efficacy of phenobarbital semi-dose loading neonate with hypoxic ischemic encephalopathy(NHIE).Methods Retrospectively analyzed the clinical datas of 71 patients with NHIE;all the patients were given phenobarbital with fractional loading for treatment.Results 69 patients(97.2%) of total 71 got better treatment,2 patients were death because of respiratory failure.Conclusion Phenobarbital semi-dose loading can better control the seizures,playing a role in the treatment of NHIE,and will not cause respiratory depression.
Keywords:Phenobarbital  Neonatal hypoxic ischemic encephalopathy  Effect
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