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分蘖洋葱化学成分及其抑菌活性
引用本文:顾承真,李婷,曾碧雪,李文娟,吴凤芝,曾任森. 分蘖洋葱化学成分及其抑菌活性[J]. 中成药, 2021, 0(4): 936-939
作者姓名:顾承真  李婷  曾碧雪  李文娟  吴凤芝  曾任森
作者单位:福建农林大学生命科学学院;福建农林大学农学院;东北农业大学园艺园林学院
基金项目:国家自然科学基金(31800332);福建农林大学杰出青年科研人才计划项目(XJQ201922)。
摘    要:目的 研究分蘖洋葱的化学成分及其抑菌活性.方法 分蘖洋葱95%乙醇提取物采用MCI、Sephadex LH-20、C18和半制备HPLC进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构.用微量稀释法测定其对番茄枯萎病病原菌生长的影响.结果 从中分离得到4个化合物,分别鉴定为槲皮素(1)、槲皮素-4'-O-β-D...

关 键 词:分蘖洋葱  化学成分  分离鉴定  抑菌活性

Chemical constituents from Allium cepa and their antifungal activity
GU Cheng-zhen,LI Ting,ZENG Bi-xue,LI Wen-juan,WU Feng-zhi,ZENG Ren-sen. Chemical constituents from Allium cepa and their antifungal activity[J]. Chinese Traditional Patent Medicine, 2021, 0(4): 936-939
Authors:GU Cheng-zhen  LI Ting  ZENG Bi-xue  LI Wen-juan  WU Feng-zhi  ZENG Ren-sen
Affiliation:(College of Life Sciences,Fujian Agriculture and Forestry University,Fuzhou 350002,China;College of Agriculture,Fujian Agriculture and Forestry University,Fuzhou 350002,China;College of Horticulture and Landscape Architecture,Northeast Agricultural University,Harbin 150030,China)
Abstract:AIM To study the chemical constituents from Allium cepa L.var.agrogatum Don.and their antifungal activity.METHODS The 95%ethanol extract of A.cepa was isolated and purified by MCI,Sephadex LH-20,C 18 and semi-preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.Their antifungal activity against pathogen of tomato Fusarium wilt was evaluated by microdilution technique.RESULTS Four compounds were isolated and identified as quercetin(1),quercetin-4′-O-β-D-glucoside(2),diasyringaresinol(3),tryptophan(4).Compounds 1-2 could inhibit the growth of pathogen of tomato Fusarium wilt,with the MIC values of 25.0,12.5μg/mL,respectively.CONCLUSION Compound 3 is isolated from this plant for the first time.Compounds 1-2 have good antifungal activity.
Keywords:Allium cepa L.var.agrogatum Don.  chemical constituents  isolation and identification  antifungal activity
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