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Mediastinal Cystic Parathyroid Adenoma Diagnosed by Somatostatin Receptor Scintigraphy
Authors:Kenichi Yokota  Isao Kurihara  Yohji Matsusaka  Katsura Emoto  Tomoyuki Hishida  Takuma Oshida  Sakiko Kobayashi  Ayano Murai-Takeda  Kazutoshi Miyashita  Kohei Matsuda  Takahiro Nakagomi  Kosuke Matsuda  Hiroshi Itoh
Affiliation:1.Department of Internal Medicine, Keio University School of Medicine, Japan; 2.Department of Nuclear Medicine, Saitama Medical University International Medical Center, Japan; 3.Department of Pathology, Keio University School of Medicine, Japan; 4.Division of Thoracic Surgery, Department of Surgery, Keio University School of Medicine, Japan
Abstract:
A 71-year-old man complained of nausea and loss of appetite for eight months prior to admission. He was transported to a hospital with disorientation and diagnosed with primary hyperparathyroidism by laboratory examinations. However, ultrasonography, computed tomography, and technetium-99m labeled methoxyisobutyl isonitrile (99mTc-MIBI) with single-photon emission computed tomography did not yield definite results. In contrast, somatostatin receptor scintigraphy successfully identified the lesion responsible for the over-secretion of parathyroid hormone within the middle mediastinum. The tumor was successfully resected by surgery, and a histopathological analysis confirmed the parathyroid adenoma nature of the tumor.
Keywords:111In-pentetreotide scintigraphy   ectopic parathyroid adenoma   parathyroid hormone   primary hyperparathyroidism   somatostatin receptor scintigraphy
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