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老年男性慢性心衰患者细胞分布宽度与心功能的关系
引用本文:胡欣,冯妹敏,李月芳,应新顺,张誉. 老年男性慢性心衰患者细胞分布宽度与心功能的关系[J]. 心血管康复医学杂志, 2012, 0(5): 552-554
作者姓名:胡欣  冯妹敏  李月芳  应新顺  张誉
作者单位:解放军第105医院干部病房,安徽合肥230031
摘    要:目的:探讨老年男性慢性心力衰竭(CHF)患者红细胞分布宽度(RDW)与心功能之间的关系。方法:入选老年男性CHF患者(CHF组)60例(NYHA心功能Ⅱ级28例,Ⅲ~Ⅳ级32例)及心功能正常的老年男性患者30例(正常对照组),分别检测RDW、红细胞计数、红细胞压积、血红蛋白含量,并行心脏彩超检查,比较不同心功能级别患者的各项指标变化。结果:与正常对照组比较,CHF组RDW明显升高[(13.85±0.6)%比(15.79±1.33)%,P<0.01],且RDW在心功能Ⅲ-Ⅳ级组较Ⅱ级组更为升高(P<0.01);E/A比值[(1.02±0.36)比(0.75±0.18)]、LVEF值[(59±9)%比(49±11)%]均明显降低(P均<0.01),且二者在心功能Ⅲ-Ⅳ级组较Ⅱ级组更为降低(P<0.01);Pearson直线相关分析显示:心衰患者RDW与E/A比值(r=-0.391,P<0.05)、LVEF值(r=-0.574,P<0.05)均呈负相关。结论:红细胞分布宽度与老年男性患者的心衰程度有关,可以间接反映老年男性CHF患者的心脏功能。

关 键 词:心力衰竭,充血性  红细胞  心室功能,左

Relationship between red cell distribution width and cardiac function in aged male patients with chronic heart failure
HU Xin,FENG Shu-min,LI Yue-fang,YING Xin-shun,ZHANG Yu. Relationship between red cell distribution width and cardiac function in aged male patients with chronic heart failure[J]. Chinese Journal of Cardiovascular Rehabilitation Medicine, 2012, 0(5): 552-554
Authors:HU Xin  FENG Shu-min  LI Yue-fang  YING Xin-shun  ZHANG Yu
Affiliation://Cadre Ward, 105th Hospital of Chinese PLA, Hefei, Anhui, 230031, China
Abstract:Objective: To study relationship between red cell distribution width (RDW) and cardiac function in aged male patients with chronic heart failure (CHF). Methods: A total of 60 aged male CHF patients [New York heart association (NYHA) cardiac function class II 28 cases and class Ⅲ - Ⅳ 32 cases1 were enrolled as CHF group, and another 30 aged male patients with normal cardiac function were regard as normal control group. RDW, red blood cell count, hematocrit and concentration of hemoglobin were measured and patients underwent color- coded Doppler echocardiography. Changes of indexes were compared among patients with different NYHA cardiac func- tion class. Results: Compared with normal control group, there was significant increase in RDW [ (13.85 ±0.6)% vs. (15.79 ± 1.33) %, P〈0. 011, and RDW in NYHA class Ⅲ- Ⅳ group was significantly higher than that of NY- HA class Ⅱ group (P〈0.01) ; There were significant decrease in ratio of early to late transmitral diastolic peak flow velocity [E/A, (1.02 ± 0.36) vs. (0.75 ±0.18)1 and left ventricular ejection fraction [.LVEF, (59 ± 9)% vs. (49 ± 11)%1 in CHF group (P〈0.01 both), and E/A and LVEF in NYHA class Ⅱ- Ⅳ group were significantly lower than those of NYHA class Ⅱ group (P〈0.01); Pearson linear correlation analysis indicated that RDW was negatively correlated with E/A (r = - 0. 391, P〈0. 05) and LVEF (r = - 0. 574, P〈0.05) in CHF patients. Conclusion: Red cell distribution width is correlated with NYHA cardiac function class in aged male patients, which can indirectly reflect cardiac function of aged male patients with chronic heart failure.
Keywords:Heart failure, congestive  Erythrocytes  Ventricular function, left
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