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| 转移相关基因CD44v6在胃癌中的表达意义 | |
| 引用本文： | 梁雨荣 何尔斯泰. 转移相关基因CD44v6在胃癌中的表达意义[J]. 中国肿瘤临床, 1999, 26(1): 33-35 |
| 作者姓名： | 梁雨荣 何尔斯泰 |
| 作者单位： | 白求恩医科大学第三临床学院基本外科 |
| 摘 要： | 目的：探讨转移相关基因ＣＤ４４ｖ６与胃癌某些生物学行为的关系。方法：采用免疫组化ＳＰ法对４２例进展期胃癌进行标记分析。结果：ＣＤ４４ｖ６阳性表达率肠型胃癌（７０．８３％）明显高于弥漫型胃癌（３３．３３％）（Ｐ〈０．０５）；淋巴结转移组（８２．３５％）明显高于无淋巴结转移组（３６．０％）（Ｐ〈０．０１）；ＣＤ４４ｖ６阳性率与肿瘤大小无关（Ｐ〉０．０５）；ＣＤ４４ｖ６阳性表达的不同病理分型的胃癌中淋巴 |
| 关 键 词： | 胃肿瘤 CD44v6 肿瘤转移 |
Significance of Expression of CD44v6 in Human Gastric Carcinoma |
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| Liang Yurong He Ersitai Third Clinical Hospital of Norman Bethune University of Medical Sciences,Changchun. Significance of Expression of CD44v6 in Human Gastric Carcinoma[J]. Chinese Journal of Clinical Oncology, 1999, 26(1): 33-35 | |
| Authors: | Liang Yurong He Ersitai Third Clinical Hospital of Norman Bethune University of Medical Sciences Changchun |
| Abstract: | The expression of CD44v6 in 42 paraffin embedded human gastric cancer tissues were studied with immunohistochemical SP technic. It was found that CD44v6 expression was present in 70.83% of intestine type cancers while it was only 33.33% in diffuse type cancers. The CD44v6 expression in cases with lymph node involvement (14/17) was significantly higher than that without (9/25). There was no association between CD44v6 expression and tumor size.These data suggest that the expression of CD44v6 is of significance in predicting the potential cancer cell metastasis. |
| Keywords: | Gastric carcinoma Gene CD44 Cancer metastasis |
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