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枢丹预防化疗所致呕吐的临床观察
引用本文:张树才,胡范彬,杨新杰. 枢丹预防化疗所致呕吐的临床观察[J]. 中国肿瘤临床, 1999, 22(3): 214-215
作者姓名:张树才  胡范彬  杨新杰
作者单位:北京结核病胸部肿瘤研究所!北京市101149
摘    要:
观察枢丹的止吐效果及毒副反应。方法对60例接受丝裂霉素,顺铂及泰素联合化疗的肺癌患者,采用随机对照的方法比较枢丹和欧必亭在相等剂量下的疗效及毒性。结论枢丹为一高效,安全的化疗止吐药。

关 键 词:枢丹 肺肿瘤 药物疗法 呕吐 预防

A Randomized Trial of Zudan in the Prophylaxis of Chemotherapy induced Nausea and Vomiting
Zhang Shucai,Hu Fanbin,Yang Xinjie,et al. A Randomized Trial of Zudan in the Prophylaxis of Chemotherapy induced Nausea and Vomiting[J]. Chinese Journal of Clinical Oncology, 1999, 22(3): 214-215
Authors:Zhang Shucai  Hu Fanbin  Yang Xinjie  et al
Abstract:
Objective: To study the anti - emetic effect of Zudan and its toxicity- Methods: A ran-domized study was done in 60 patients with lung cancer who received Mitomycin C, Cisplatin and Taxolchemotherapy comparing the efficacy and the toxicity of identical dosage of Zudan and Navoban. Results:The response rate of emesis induced was 83. 3% in patients receiving Zudan and 80. 0% in those receiv-ing Navoban. Complete response rate was 73. 3% in the Zudan arm and 66. 7% in the Navoban arm.The two arms were not markedly different in response rates. The mild toxicity of the two antiemetics wereobserved. Conclusion: Zudan was safe and effective in the control of chemotherapy induced emesis.
Keywords:Zudan  Navoban  Emesis  Lungcancer  Chemotherapy
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