解毒利湿方联合西药治疗肝胆湿热慢性乙型肝炎随机平行对照研究

[目的]观察解毒利湿方联合西药治疗肝胆湿热慢性乙型肝炎疗效。[方法]使用随机平行对照方法,将80例门诊患者按抛硬币法简单随机分为两组。对照组40例抗病毒、护肝等治疗。治疗组40例解毒利湿方(红景天、绵茵陈、半枝莲各20g,桑葚、荷叶、田基黄各15g,黄连、清半夏、柴胡各12g),1剂/d,水煎400mL,早晚口服;西药治疗同对照组。连续治疗7d为1疗程。观测临床症状、ALT、AST、ALP、不良反应。连续治疗4疗程,判定疗效。[结果]治疗组痊愈25例,有效13例,无效2例,总有效率95.00%。对照组痊愈17例,有效10例,无效13例,总有效率67.50%。治疗组疗效优于对照组(P0.01)。ALT、AST、ALP指标两组均有降低(P0.01),治疗组降低幅度大于对照组(P0.01)。[结论]解毒利湿方联合西药在治疗肝胆湿热慢性乙型肝炎疗效显著,值得推广。

Chronic Hepatitis B Liver and Gallbladder Damp-heat Syndrome Randomized Parallel Group Study Combined with Western Medicine Detoxification Dampness

[ Objective ] To observe the combined western side dampness detoxification therapy of chronic hepatitis B liver and gallbladder damp-heat syndrome. E Methods ] Random parallel control method, 80 outpatients were randomly divided into two groups. Western medicine control group of 40 patients, antiviral drugs, liver drugs and other treatment. Dampness detoxification treatment group, 40 cases of side （ Hongjingtian, Mianyinchen, Banzhilian each 20g, Sangshen, Heye, Tianjihuang each 15g, Huanglian, Qingbanxia, Chaihu each 12g ）, 1 a / d, decoction 400mL, sooner or later, oral;western medicine with the control group. 7d is a continuous course of treatment. Observation of clinical symptoms, ALT, AST and ALP indicators adverse reactions. 4 continuous treatment regimen to determine efficacy. [ Results ] The cure 25 cases, effective in 13 cases, 2 cases, the total efficiency of 95.00%. Cured 17 cases in the control group, 10 cases, ineffective in 13 cases, the total efficiency of 67.50%. Treatment group than the control group （P 〈0.01 ） . ALT, AST and ALP two indicators were lower （ P〈0.01 ）, reducing the magnitude of the treatment group than the control group （ P〈0.01 ） . [ Conclusion ] detoxification dampness combined western side gallbladder damp-heat syndrome in chronic hepatitis B treatment effect is significant, it is worth promoting.