| 高血压病患者vWF及胰岛素抵抗与中医证型的关系 |
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| 引用本文： | 张雪梅,符德玉,王世红,何淑寅,祖亮华,辛效毅,赵彦功.高血压病患者vWF及胰岛素抵抗与中医证型的关系[J].辽宁中医杂志,2010(2):200-202. |
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| 作者姓名： | 张雪梅 符德玉 王世红 何淑寅 祖亮华 辛效毅 赵彦功 |
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| 作者单位： | 上海中医药大学附属岳阳中西医结合医院; |
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| 基金项目： | 国家中医药管理局资助项目(04-05-JL07) |
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| 摘 要： | 目的:探讨高血压病患者血管性血友病因子(vWF)及胰岛素抵抗(IR)与中医证型之间的关系。方法:将124例高血压患者进行中医辨证分型,测定BMI、血压、空腹血糖、空腹胰岛素、血浆vWF,同时计算IR的程度,IR采用HOMA-IR,并对vWF及IR进行相关分析。结果:患者空腹胰岛素水平在各证型之间存在显著差异,肝火亢盛组显著高于阴虚阳亢组及痰湿壅盛组(P0.01);肝火亢盛组IR显著高于痰湿壅盛组(P0.01),各组间IR水平为肝火亢盛组阴阳两虚组阴虚阳亢组痰湿壅盛组;高血压病患者阴阳两虚组血浆vWF水平显著高于其他3组,且vWF与年龄呈正相关(R=0.308,P0.01)。年龄每上升1岁,vWF水平上升0.978Mu/mL。结论:高龄高血压患者可能存在血管内皮损伤,更易血栓形成;肝火亢盛组IR最高,提示有明显的糖代谢紊乱。
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| 关 键 词： | 高血压 胰岛素抵抗 vWF 中医证型 |
The Relationship Among Plasma vWF Insulin Resistance and TCM Syndromes in Hypertension |
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| ZHANG Xue-mei,FU De-yu,WANG Shi-hong,HE Shu-yin,ZU Liang-hua,XIN Xiao-yi,ZHAO Yan-gong.The Relationship Among Plasma vWF Insulin Resistance and TCM Syndromes in Hypertension[J].Liaoning Journal of Traditional Chinese Medicine,2010(2):200-202. |
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| Authors: | ZHANG Xue-mei FU De-yu WANG Shi-hong HE Shu-yin ZU Liang-hua XIN Xiao-yi ZHAO Yan-gong |
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| Institution: | Yueyang Hospital Affiliated to Shanghai University of TCM/a>;Shanghai 200437/a>;China |
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| Abstract: | Objective:To discuss the relationship among plasma vWF,insulin resistance and TCM syndromes in hypertension.Methods:One hundred and twenty-four patients with hypertension were selected and differentiated TCM syndromes.BMI,BP,fasting blood-glucose,fasting insulin and plasma vWF were detected.IR is evaluated by fasting blood-glucose value and fasting insulin level.The correlation of vWF with IR is analyzed.Results:There exists significant difference among the patients' fasting insulin level in different TCM s... |
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| Keywords: | Hypertension insulin resistance vWF TCM syndrome |
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