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绝经前后血清雌激素水平与瘦素之间关系的探讨
引用本文:刘树琴,丁晓颖,章秋,储小宏,叶志恒,邵宜波.绝经前后血清雌激素水平与瘦素之间关系的探讨[J].生殖医学杂志,2002,11(6):339-342.
作者姓名:刘树琴  丁晓颖  章秋  储小宏  叶志恒  邵宜波
作者单位:1. 安徽医科大学附属第一医院内分泌科,合肥,230022
2. 天津医科大学总医院内分泌科,天津,300052
基金项目:安徽省卫生厅科研基金资助课题 (卫科字 199815 0)
摘    要:目的 :探讨绝经前后血清雌激素水平与瘦素之间的关系。方法 :本研究从绝经前后、绝经后有无接受激素替代治疗 ( HRT)及绝经前有无应用避孕药 3个方面进行横断面研究。共收集 92例绝经前、后妇女的临床资料 ,采用放射免疫法测定血清雌激素及瘦素水平 ,所得数据进行统计学分析。结果 :绝经前、后 ,绝经后有无接受 HRT,绝经前有无避孕药应用史组间瘦素水平均无显著性差异。结论 :绝经前后血清瘦素水平同雌激素无直接关联 ,绝经后妇女接受短期 HRT对瘦素水平无影响

关 键 词:雌激素  瘦素  绝经
文章编号:1004-3845(2002)06-0339-04
修稿时间:2002年1月29日

Study on the relationship between estrogen levels and leptin concentrations in women before and after menopause
LIU Shu-qin,DING Xiao-ying ,ZHANG Qiu,CHU Xiao-hong,YE Zhi-heng,SHAO Yi-bo Division of Endocrinology,The First Affiliated Hospital to An Hui Medical University,Hefei Division of Endocrinology,The General Hospital to Tianjin Medical University,Tianjin.Study on the relationship between estrogen levels and leptin concentrations in women before and after menopause[J].Journal of Reproductive Medicine,2002,11(6):339-342.
Authors:LIU Shu-qin  DING Xiao-ying  ZHANG Qiu  CHU Xiao-hong  YE Zhi-heng  SHAO Yi-bo Division of Endocrinology  The First Affiliated Hospital to An Hui Medical University  Hefei Division of Endocrinology  The General Hospital to Tianjin Medical University  Tianjin
Institution:LIU Shu-qin,DING Xiao-ying *,ZHANG Qiu,CHU Xiao-hong,YE Zhi-heng,SHAO Yi-bo Division of Endocrinology,The First Affiliated Hospital to An Hui Medical University,Hefei 230022 *Division of Endocrinology,The General Hospital to Tianjin Medical University,Tianjin 300052
Abstract:Objective: To explore the relationship between serum estrogen levels and leptin concentrations in women before and after menopause. Methods: The study was carried out in 92 women. There are 22 premenopausal women with or without taking contraceptive and 70 postmenopausal women with or without hormone replacement therapy. Serum leptin levels and estrogen concentrations were determined by radioimmunoassay. These data were processed with analysis of variance, correlation and multiple stepwise regression. Results: The results showed that leptin levels were not statistically significantly different between above mentioned groups.Conclusion: This study indicates that leptin concentration is not directly related to estrogen level. Short-term HRT appears no any effect on the serum leptin level.
Keywords:Estrogen  Leptin  Menopause
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