田七注射液治疗慢性肾功能衰竭疗效观察

目的:研究田七注射液在治疗慢性肾功能衰竭中的作用。方法:选择符合诊断标准的CRF患者52例,随机分为治疗组28例及对照组24例,两组病例在常规治疗的基础上,治疗组予以田七注射液静脉滴注,对照组予以肾安注射液静脉滴注,以4周为1疗程,观察治疗前后两组患者血脂及肾功能的变化。结果:治疗组总有效率为85.71%,优于对照组的58.33%,两组比较差异有显著性意义(P<0.01)。治疗组治疗后血清总胆固醇(TC),甘油三酯(TG),低密度脂蛋白(LDL)明显降低(P<0.01或P<0.05),且优于对照组(P<0.01),对照组TC、高密度脂蛋白(HDL)治疗后改善不明显;两组治疗后各项肾功能指标均有改善,治疗组疗效优于对照组(P<0.01或P<0.05)。结论:田七注射液能明显改善CRF患者血脂及肾功能,延缓CRF进程,值得临床推广应用。

Effect of Tianqi Injection in Patients with Chronic Renal Failure

Objective:To investigate the effect of Tianqi Injection in patients with chronic renal failure(CRF). Methods:52 patients with CRF were randomized into the treating group(n=28) and the control group(n=24). Base on the routine therapy, Tianqi Injection was used to the treating group additionally, and Amino Acid Injection was used to the control group, 4 weeks constituted one treatment course. The changes of blood-lipid and renal function were observed before and after treatment. Results:The total effective rate was 85.71% in treating group and 58.33% in control group (P<0.01). After treatment, the serum levels of total cholesterol(TC),triglycerides (TG) ,and low density lipoprotein (LDL) were decreased in treating group (P<0.01 or P<0.05), and the effect was better than that in the control group(P<0.01). TG and high density lipoprotein (HDL) in control group after treatment did not differ from those before treatment. The levels of BUN and Scr were significantly decreased in 2 groups after treatment, and the effect of treating group was better than that in the control group(P<0.01 or P<0.05). Conclusion:Tianqi Injection could delay CRF progression by improving the blood-lipid and renal function of patients with CRF. It was worth applying to clinical therapy further.