The syndrome of inappropriate secretion of antidiuretic hormone in children with bacterial meningitis |
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Authors: | S L Kaplan R D Feigin |
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Affiliation: | 1. Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine St. Louis, Mo. USA;2. Division of Infectious Diseases, at St. Louis Children''s Hospital St. Louis, Mo. USA |
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Abstract: | Plasma concentrations of arginine vasopressin were determined by radioimmunoassay in 13 normal children, 21 patients with febrile illnesses (not bacterial meningitis), and 17 patients with bacterial meningitis. The mean +/- 1 SD concentrations of AVP in the normal children and patients with various febrile illnesses were 0.7 +/- 0.6 and 1.0 +/- 1.2 muU/ml, respectively. The mean +/- 1 SD concentration of AVP in patients with bacterial meningitis was 3.3 +/- 2.3 muU/ml. The concentrations of AVP in the patients with bacterial meningitis were significantly greater (P less than 0.001) than those noted in the normal children or children with other febrile diseases. |
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Keywords: | Reprint address: Department of Pediatrics Baylor College of Medicine 1200 Moursund Ave. Houston TX 77030. |
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