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| 脑出血患者血清神经元特异性烯醇化酶的动态变化和意义 | |
| 引用本文： | 杨霄鹏,李秋芳,杨瑞玲.脑出血患者血清神经元特异性烯醇化酶的动态变化和意义[J].中国实用神经疾病杂志,2008,11(9):37-39. |
| 作者姓名： | 杨霄鹏 李秋芳 杨瑞玲 |
| 作者单位： | 1. 郑州大学第二附属医院神经内科,郑州,450014 2. 郑州大学护理学院临床教研室,郑州,450000 3. 河南大学附属东京医院药剂科,开封,475001 |
| 摘 要： | 目的研究脑出血患者血清中神经元特异性烯醇化酶(NSE)动态变化的临床价值。方法采用酶联免疫吸附法对48例脑出血患者起病第1、3、7、14d血清NSE水平进行动态测定,神经功能缺损按斯堪的纳维亚卒中量表(SSS)标准进行评定。结果脑出血组各时间血清NSE水平明显高于对照组(P<0.001),并与出血量大小及SSS呈正相关。结论血清NSE的水平变化对判断脑出血量大小和预后有重要参考价值。 |
| 关 键 词： | 脑出血 神经元特异性烯醇化酶 斯堪的纳维亚卒中量表 |
Dynamic changes and significance of serum neuron specific enolase during acute period in patients with intracerebral hemorrhage |
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| Yang Xiaopeng,Li Qiufang,Yang Ruiling.Dynamic changes and significance of serum neuron specific enolase during acute period in patients with intracerebral hemorrhage[J].Chinese Journal of Practical Neruous Diseases,2008,11(9):37-39. | |
| Authors: | Yang Xiaopeng Li Qiufang Yang Ruiling |
| Abstract: | Objective To investigate the dynamic changes and clinical significance of serum neuron specific enolase(NSE) in patients with intracerebral hemorrhage(ICH).Methods The serum NSE of 48 patients with ICH was tested by ELISA at 1,3,7 and 14 days after the hemorrhage happened.Neurological function dificit were valued with Scandivia stroke scale(SSS).Results The serum levels of NSE were higher in ICH group than that in control group(P<0.001) and were positively correlated with the volumes of hematoma and SSS.Conclusion The serum NSE test in the patients with ICH is very useful to judging the volume of the hemorrhage and the prognosis. |
| Keywords: | Intracerebral hemorrhage Neuron specific enolase Scandivian stroke scale |
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