| 近红外光谱法快速分析不同厂家炒栀子配方颗粒的质量 |
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| 引用本文： | 孙胜斌,陈翔宇,高晗,姜国志,李军山,李振江.近红外光谱法快速分析不同厂家炒栀子配方颗粒的质量[J].中国现代应用药学,2015,32(8):960-963. |
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| 作者姓名： | 孙胜斌 陈翔宇 高晗 姜国志 李军山 李振江 |
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| 作者单位： | 神威药业集团有限公司，石家庄 051430；中药注射剂新药技术开发国家地方联合工程实验室，石家庄 051430,河北省中药注射液液剂工程技术研究中心，石家庄 051430,神威药业集团有限公司，石家庄 051430,中药注射剂新药技术开发国家地方联合工程实验室，石家庄 051430,神威药业集团有限公司，石家庄 051430,神威药业集团有限公司，石家庄 051430 |
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| 基金项目： | 国家中医药管理局中医药科学技术研究专项项目(国中医药科2013ZX07) |
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| 摘 要： | 目的 考察不同厂家炒栀子配方颗粒的质量。方法 利用近红外光谱仪直接对各厂家样品进行积分球漫反射全波长扫描，用马氏距离法分类建模，计算不同厂家配方颗粒间的距离。结果 A、B、C厂家炒栀子配方颗粒间距离均较大，相互间区别明显。结论 不同厂家生产的炒栀子配方颗粒质量相互间有一定差异。
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| 关 键 词： | 近红外光谱法 炒栀子 配方颗粒 质量 |
| 收稿时间： | 4/6/2015 12:00:00 AM |
| 修稿时间： | 8/5/2015 12:00:00 AM |
Rapid Analysis of the Quality of Formula Granule of Stir-baked Gardeniae Fructus Formula from Different Manufacturers by Near-infrared Spectroscopy |
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| SUN Shengbin,CHEN Xiangyu,GAO Han,JIANG Guozhi,LI Junshan and LI Zhenjiang.Rapid Analysis of the Quality of Formula Granule of Stir-baked Gardeniae Fructus Formula from Different Manufacturers by Near-infrared Spectroscopy[J].The Chinese Journal of Modern Applied Pharmacy,2015,32(8):960-963. |
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| Authors: | SUN Shengbin CHEN Xiangyu GAO Han JIANG Guozhi LI Junshan and LI Zhenjiang |
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| Institution: | Shineway Pharmaceutical Group Co., Ltd., Shijiazhuang 051430, China; State-local Joint Engineering Laboratory of New Drugs Development Technology for TCM Injection, Shijiazhuang 051430, China,Hebei Province Engineering Research Center for TCM Injection, Shijiazhuang 051430, China,Shineway Pharmaceutical Group Co., Ltd., Shijiazhuang 051430, China,State-local Joint Engineering Laboratory of New Drugs Development Technology for TCM Injection, Shijiazhuang 051430, China,Shineway Pharmaceutical Group Co., Ltd., Shijiazhuang 051430, China and Shineway Pharmaceutical Group Co., Ltd., Shijiazhuang 051430, China |
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| Abstract: | OBJECTIVE To analyse the quality of formula granule of stir-baked Gardeniae Fructus from different manufacturers. METHODS Integrating sphere diffuse full-wavelength scanning of samples from different manufacturers were measured by near-infrared spectroscopy. Mahalanobis distance was used to categoriz modeling and calculate the distance between different manufacturers. RESULTS The distances of formula granule of stir-baked Gardeniae Fructus formula produced by A, B and C were obviously different. CONCLUSION There are certain diversities of quality of formula granule of stir-baked Gardeniae Fructus from different manufacturers. |
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| Keywords: | near-infrared spectroscopy stir-baked Fructus Gardeniae formula granule quality |
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