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| 特发性肺纤维化的发病机制及药物治疗研究进展 | |
| 引用本文： | 满红霞,肖培云,杨永寿,那凯歌,谭巧云. 特发性肺纤维化的发病机制及药物治疗研究进展[J]. 中国现代应用药学, 2015, 32(8): 1024-1028 |
| 作者姓名： | 满红霞 肖培云 杨永寿 那凯歌 谭巧云 |
| 作者单位： | 大理大学药学与化学学院，云南 大理 671000,大理大学药学与化学学院，云南 大理 671000,云南省昆虫生物医药研发重点实验室，云南 大理 671000,大理大学药学与化学学院，云南 大理 671000,大理大学药学与化学学院，云南 大理 671000 |
| 基金项目： | 国家自然科学基金项目(81360634、81060329)；云南省教育厅科学研究基金项目(2011Z053)；云南省科技计划项目(2015FA025) |
| 摘 要： | 特发性肺纤维化是一种以两肺间质纤维化伴蜂窝状改变为特征的疾病，其发病率及死亡率逐年增高，且生存期较短，愈后极差，几乎与恶性肿瘤无异。因此，特发性肺纤维化发病机制和治疗也成为国际医学界的研究热点。本文就其病发机制和药物治疗研究进展进行了综述，为今后的进一步研究提供参考。 |
| 关 键 词： | 特发性肺纤维化；发病机制；细胞因子；药物治疗 |
| 收稿时间： | 2014-11-05 |
| 修稿时间： | 2015-07-29 |
Pathogenesis of Idiopathic Pulmonary Fibrosis and Its Advances in Cytokine Treatment |
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| MAN Hongxi,XIAO Peiyun,YANG Yongshou,NA Kaige and TAN Qiaoyun. Pathogenesis of Idiopathic Pulmonary Fibrosis and Its Advances in Cytokine Treatment[J]. The Chinese Journal of Modern Applied Pharmacy, 2015, 32(8): 1024-1028 | |
| Authors: | MAN Hongxi XIAO Peiyun YANG Yongshou NA Kaige TAN Qiaoyun |
| Affiliation: | College of Pharmacy and Chemistry, Dali University, Dali 671000, China,College of Pharmacy and Chemistry, Dali University, Dali 671000, China,Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali 671000, China,College of Pharmacy and Chemistry, Dali University, Dali 671000, China and College of Pharmacy and Chemistry, Dali University, Dali 671000, China |
| Abstract: | Idiopathic pulmonary fibrosis is a kind of two pulmonary fibrosis disease characterized with honeycomb change, its incidence and mortality rate increased year by year, and lifetime is short, the poor prognosis is almost the same with malignant tumor. Therefore, pathogenesis and treatment of idiopathic pulmonary fibrosis has become the focus in the international medical community. The paper reviewed the disease mechanism and drug treatment research progress, to provide a reference for the further research. |
| Keywords: | idiopathic pulmonary fibrosis pathogenesis cytokines clinical medication |
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