| 中枢5-羟色胺在针刺效应中的作用研究进展 |
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| 引用本文： | Hu WB,Wu ZJ,Wang KM. 中枢5-羟色胺在针刺效应中的作用研究进展[J]. 针刺研究, 2012, 37(3): 247-251 |
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| 作者姓名： | Hu WB Wu ZJ Wang KM |
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| 作者单位： | 安徽中医学院针灸经络研究所 |
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| 基金项目： | 国家自然科学基金(30801484);安徽省自然科学基金(090413112);安徽高校省级自然科学研究项目(KJ 2011A188);安徽中医学院科学研究基金(2010zr 016B)资助 |
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| 摘 要： | 5-羟色胺作为参与针刺效应的重要中枢调控物质,在阐述针刺效应作用机制中有着重要的研究价值。大量实验研究已证明针刺能显著影响中枢5-羟色胺的含量及活动,且不同条件下针刺对5-羟色胺影响不同。本文就近年来国内外中枢5-羟色胺及其受体在针刺效应中的作用研究现状作了回顾,并结合以往的研究提出新的看法和研究思路。
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| 关 键 词： | 5-羟色胺 中枢神经系统 针刺镇痛 电针 |
Progress of researches on involvement of serotonin in the central nervous system in acupuncture analgesia and other effects |
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| Hu Wu-Bin,Wu Zi-Jian,Wang Ke-Ming. Progress of researches on involvement of serotonin in the central nervous system in acupuncture analgesia and other effects[J]. Acupuncture research, 2012, 37(3): 247-251 |
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| Authors: | Hu Wu-Bin Wu Zi-Jian Wang Ke-Ming |
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| Affiliation: | Institute of Acu-moxibustion and Meridian, Anhui College of Traditional Chinese Medicine, Hefei 230038, China. |
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| Abstract: | As for an important central regulatory neurotransmitter involving acupuncture effect, serotonin (5-HT) is worthy of being paid with more attention. In the present paper, the authors review development of researches on the involvement of 5-HT and its receptor subunits in pain perception, acupuncture analgesia, and other effects of acupuncture (anti-depression, weight-reduction, etc.). Many studies showed that acupuncture intervention could modulate the content and activity of central 5-HT, and these changes varied under different conditions. Hence, the relationship between 5-HT and other neurotransmitters in acupuncture analgesia and its different functions in different regions of the central nervous system should be considered comprehensively. |
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| Keywords: | Serotonin Central nervous system Acupuncture analgesia Electroacupuncture |
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