前列腺副神经节瘤1例报道并文献复习

目的:探讨前列腺副神经节瘤的临床表现、病理特征、治疗和预后。方法:报道前列腺副神经节瘤1例,患者男,39岁,主因"反复血精1年余"入院,误诊为前列腺癌后,行耻骨上前列腺根治性切除术,完整切除肿瘤。结果:术后病理确诊为前列腺副神经节瘤,本例前列腺副神经节瘤为无功能性,免疫组化:NSE(+)、CGA(+)、S100(+)、CK(-)、Desmin(-)。术后血压平稳,2周后拔尿管出院。随访48个月至今未复发。结论:前列腺副神经节瘤缺乏特异的临床特征表现,易误诊,只有靠切除术后病理和免疫组化才能确诊。由于其非常罕见,相关治疗缺乏成熟的经验,故需要进一步研究。

Paraganglioma of the prostate: a case report and review of the literature

Objective: To investigate the clinical presentation,pathologic features,treatment and prognosis of prostatic paraganglioma.Methods: We retrospectively studied a case of prostatic paraganglioma and reviewed relevant literature.The patient was a 39-year-old man,admitted for repeated hemaspermia for over 12 months.After misdiagnosed as having prostate cancer,he underwent suprapubic prostatectomy,with the tumor completely removed.Results: Postoperative pathological examination confirmed the tumor to be prostatic paraganglioma,which was non-functional,with the immunohistochemical results of NSE(+),CGA(+),S100(+),CK(-) and Desmin(-).Postoperative blood pressure was stable.Two weeks after surgery,the urethral catheter was removed and the patient discharged.No recurrence was found during 48 months of follow-up.Conclusion: Lacking specific clinical characteristics,paraganglioma of the prostate is easily misdiagnosed,and can be confirmed only by postoperative pathology and immunohistochemistry.For the treatment of this rare tumor,little experience has been accumulated,and further studies are needed.