Differential effects of d-amphetamine on fixed ratio 30 performance maintained by food versus brain stimulation reinforcement |
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| Authors: | R J Carey E B Goodall G F Procopio |
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| Affiliation: | Veterans Administration Hospital and State University of New York Upstate Medical Center, Syracuse, N.Y. 13210, USA;Department of Psychology, Syracuse University, Syracuse, N.Y. 13210, USA;Veterans Administration Hospital, Syracuse, N.Y. 13210, USA |
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| Abstract: | Four rats with implanted unilateral hypothalamic bipolar electrodes were trained to bar press for both intracranial self-stimulation (ICSS) and food on a fixed ratio 30 schedule of reinforcement. The animals were tested at 90% and 100% body weight. d-Amphetamine (0.1, 0.5, 1.0, 1.5, 2.0 mg/kg) always decreased responding for blood reinforcement but increased responding up through the 1.0 mg/kg dose level for ICSS. An analysis of error responses emitted for ICSS reinforcement showed that perseverative responding did not occur up through the 1.0 mg/kg level. |
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| Keywords: | d-Amphetamine Fixed ratio Food Brain stimulation |
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