Successful salvage therapy of irinotecan for relapsed Hodgkin's lymphoma |
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| Authors: | Urushihata Kazuhisa Koizumi Tomonobu Kaneki Toshimichi Yamaguchi Shinji Fujimoto Keisaku Kubo Keishi |
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| Affiliation: | First Department of Medicine, Shinshu University, Matsumoto. |
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| Abstract: | A 30-year-old man, who had a repeated history of relapsed Hodgkin's lymphoma over 7 years, developed bilateral pleural effusion and chest wall involvement. He was treated with weekly irinotecan hydrochloride (CPT-11; 80 mg/m2/week). Partial response was observed after two cycles of irinotecan. Neutropenia and diarrhea were tolerable. This case demonstrated that irinotecan has a therapeutic effect in patients with relapsed Hodgkin's lymphoma. |
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