黄芪、复方丹参注射液对肝硬化患者红细胞体积分布宽度的影响

目的　观察黄芪、复方丹参注射液对肝硬化患者治疗前后红细胞体积分布宽度的影响。方法　将 6 5例肝硬化患者随机分为治疗组和对照组。治疗组给予黄芪及复方丹参注射液 ,对照组给予复方丹参注射液 ,均每日 1次 ,治疗 3个月 ,并与健康人做对照。结果　两组治疗前红细胞体积分布宽度标准差 (RDW SD)和红细胞体积分布宽度变异系数 (RDW CV)均显著高于健康人 (P <0 0 0 1) ,治疗后治疗组明显降低 (P <0 0 1) ,治疗组优于对照组 (P <0 0 5 ) ,治疗组治疗后肝功能丙酮酸氨基转移酶 (ALT)、门冬氨基转移酶 (AST)及球蛋白 (Glb)均显著降低 (P <0 0 1) ,白蛋白 (Alb)较治疗前升高 (P <0 0 5 ) ,以治疗组为优。结论　黄芪、复方丹参注射液具有改善红细胞变形能力 ,恢复肝功能 ,促进肝病恢复等作用。

Effect of Root of Membranous Milkvetch and Fufangdanshen Injectionon RDW in Cirrhosis Patients

objective To observe the effect on RDW in cirrhosis patients before and after the treatment with root of membranous milkvetch and Fufangdanshen Injection. Method Sixty-five patients with cirrhosis were randomly divided into the treatment group treated with root of membranous milkvetch and Fufangdanshen Injection and the control group treated with Fufangdanshen Injection only. Both were treated once a day for 3 months. They were also compared with normal people. Result Before the treatment RDW-SD and RDW-CV of the patients in two groups were all obvious higher than that of normal people. After the treatment RDW-SD and RDW-CV of the patients were lower distinctly in the treatment group (P<0.01), so the effect of the treatment group was better than that of the control group (P<0.05). In the treatment group ALT, AST and Glb of the patients were all significant reduced after the treatment (P<0.01), and Alb was increased than that before the treatment (P<0.05). The effect on the treatment group was better. Conclusion Root of membranous milkvetch and Fufangdanshen Injection have ability to relieve RDW, recover liver function and promote cure of liver disease.