Flap-free LASEK和Flap-free Epi.LASIK治疗中、低度近视临床效果比较

目的比较Flap-free LASEK（去上皮瓣的准分子激光上皮瓣下角膜磨镶术）和Flap-free Epi.LASIK（去上皮瓣的机械法准分子激光角膜上皮辦下磨镶术）治疗中、低度近视的临床效果。方法将78位患者143只眼（-1.50D～-6.00D）,随机分为2组A组和B组,A组行Flap-free LASEK,B组行Flap-free Epi.LASIK术式。观察术后眼球疼痛症状、角膜上皮愈合时间和术后1、3、6个月裸眼视力及haze情况。结果 A、B2组术后3d眼球疼痛刺激症状1、2、3级例数的差异无统计学意义。A组平均角膜上皮愈合时间为（3.81±0.07）d,B组平均为（4.15±0.12）d,2者差异有统计学意义（t=2.42,P〈0.05）,术后1、3、6个月时视力和haze2组比较无统计学意义。结论 Flap-free LASEK矫正中、低度近视与Flap-free Epi.LASIK相比较,角膜上皮愈合更快,术后疼痛刺激、视力恢复和haze的形成二者无明显差异。

Clinical Evaluation of Flap-free LASEK and Flap-free Epi.LASIK on the Treatment of Moderate and Low Myopia

Objective To contrast the clinical efficacy of Flap-free LASEK and Flap-free Epi.LASIK for low and moderate myopia.Methods Seventy eight patients with 143 eyes（-1.50D～-6.00D） were divided randomly into two groups.All subjective pain scores were evaluated on the third postoperative day.The days of corneal epithelium healing were recorded.The Uncorrected visual acuity（UCVA） and haze scores were detected in 1,3,6 months after surgery.Results Scores of pain was no obvious difference in group A and B on the third day postoperatively,while the day of corneal healing was significant difference in group A and B（t=2.42,P0.05）.The average day of epithelium well reconstruction was shorter in the group of the A（3.81±0.07）,and longer in group B（4.15±0.12）.The difference of the UCVA and haze scores were no statistical significance in 1,3,6 months after surgery between the two groups.Conclusion The cornea epithelium well reconstruction was faster in Flap-free LASEK than that in Flap-free Epi.LASIK.There was no obviously difference in pain score,UCVA and haze score between the two groups.