Nonalcoholic Fatty Liver Disease: Pathogenesis, Identification, Progression, and Management |
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| Authors: | Eric Yan MD Francisco Durazo MD Myron Tong MD PhD Kurt Hong MD PhD |
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| Affiliation: | Center for Human Nutrition, David Geffen School of Medicine, University of California, Los Angeles, CA, USA;Division of Digestive and Liver Diseases, Pfleger Liver Institute, David Geffen School of Medicine, University of California, Los Angeles, CA, USA. |
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| Abstract: | ![]()
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of liver diseases in the absence of significant alcohol consumption, and its incidence is paralleling the increasing numbers of overweight and obese individuals worldwide. This review discusses the pathogenesis of NAFLD, including the roles potentially played by specific adipokines, such as TNF-α, leptin, and adiponectin. Clinical features, diagnosis, and potential methods of management are also addressed to assist practitioners with the management of this growing population of patients. |
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| Keywords: | adipokines management nonalcoholic fatty liver disease nonalcoholic steatohepatitis |
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