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| 微乳在注射给药系统中的应用研究进展* | |
| 引用本文： | 吴蕾,桂双英. 微乳在注射给药系统中的应用研究进展*[J]. 中国新药杂志, 2007, 16(23): 1927-1929 |
| 作者姓名： | 吴蕾 桂双英 |
| 作者单位： | 1. 安徽中医学院药学院,合肥,230031 2. 安徽中医学院药学院,合肥,230031;安徽省现代中药研发创新团队,合肥,230031 |
| 基金项目： | 安徽省优秀青年科技基金计划 |
| 摘 要： | 微乳是热力学稳定的液-液分散体系,粒径在10~100 nm之间,它作为新型给药系统,由于其具有增溶、缓释、提高生物利用度等显著优点,在口服、经皮、注射给药方面均有广泛应用研究。更由于其低黏度,可直接注射,以及靶向的特性在注射给药方面显示出独特的优势。现对微乳在注射给药系统中的应用研究进展进行综述。 |
| 关 键 词： | 微乳 注射给药系统 靶向 |
| 文章编号： | 1003-3734（2007）23-1927-04 |
| 收稿时间： | 2007-08-20 |
| 修稿时间： | 2007-08-20 |
Advances on microemulsion application in injection delivery systems |
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| WU Lei,GUI Shuang-ying. Advances on microemulsion application in injection delivery systems[J]. Chinese Journal of New Drugs, 2007, 16(23): 1927-1929 | |
| Authors: | WU Lei GUI Shuang-ying |
| Abstract: | Microemulsion is a liquid-liquid dispersant system which is thermodynamically stable, the particle size is between 10 - 100 nm. The research on microemulsion used as novel drug delivery system has been arising from 1990 s. Microemulsion is extensively applied on oral, transdermal and injection drug delivery because it is solube, sustained release and can improve bioavailability of water-insoluble drugs. And it has more advantages on injection delivery because of its low viscosity and targeting character. This paper makes a systematic review about the application of microemulsion on the injection administration after review of recently microemulsion literatures. |
| Keywords: | microemulsion injection delivery systems targeting |
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| 点击此处可从《中国新药杂志》浏览原始摘要信息 | |