妊娠晚期孕妇B族链球菌感染的研究状况

B族链球菌(GBS)是孕产妇生殖道感染的重要致病菌,与早产、胎膜早破、产褥感染、新生儿败血症等疾患有关。GBS在妊娠早中期尚不能直接侵入羊膜腔引起宫内感染,无需过早干预,宜在孕35～37周取标本筛查。检测方法有培养、细菌抗原检测、PCR等,各种检测方法各有优缺点,可根据需要选择合适方法。对于GBS的预防治疗,一般推荐青霉素注射,不适应者再根据药敏结果选择治疗。

Research on Group B Streptococcal Infection in Third Trimester Pregnant Women

Group B Streptococcus(GBS)are important pathogens of reproductive tract infection in pregnancy,related to prematurity delivery,premature rupture of membranes,puerperal infection,neonatal sepsis and other diseases.GBS in early and middle period of pregnancy is not a direct invasion of amniotic cavity caused by intrauterine infection,premature intervention is not needed,specimens should be taken for screening in the 35-37 week of gestation.Test methods include cultivation,bacterial antigen detection,PCR,and so on,each with advantages and disadvantages respectively,the appropriate method should be chosen depending on the need.For the preventive treatment of GBS,penicillin injection is often recommended,and treatment of the unadapted should be selected according to the antibiotic susceptibility result.