| 亚临界水提取法提取黄连中的4种生物碱 |
| |
| 引用本文： | 卢佳,张素娟,钱广生,李章万,付春梅. 亚临界水提取法提取黄连中的4种生物碱[J]. 华西药学杂志, 2008, 23(6) |
| |
| 作者姓名： | 卢佳 张素娟 钱广生 李章万 付春梅 |
| |
| 作者单位： | 四川大学华西药学院,四川,成都,610041;四川大学华西药学院,四川,成都,610041;四川大学华西药学院,四川,成都,610041;四川大学华西药学院,四川,成都,610041;四川大学华西药学院,四川,成都,610041 |
| |
| 摘 要： | 目的 建立黄连中小檗碱、巴马汀、黄连碱和药根碱4种生物碱的亚临界水提取方法.方法 分别考察了提取温度、时间和溶剂样品比以及提取次数对提取量的影响,并与有机溶剂提取法进行比较.结果 4种生物碱的亚临界水提取法的最佳条件为:溶剂样品比0.08 ml·mg-1、提取温度140℃、5 MPa提取两次,每次5 min,提取回收率大于97.7%(n=3).结论 亚临界水提取法较传统溶剂提取法,提取时间缩短,避免了使用有机溶剂造成的污染,可用于黄连生物碱的工业化提取.
|
| 关 键 词： | 亚临界水提取 黄连 生物碱 |
Subcritical water extraction of alkaloids from Coptis chinensis Franch |
| |
| LU Jia,ZHANG Su-juan,QIAN Guang-sheng,LI Zhang-wan,FU Chun-mei. Subcritical water extraction of alkaloids from Coptis chinensis Franch[J]. West China Journal of Pharmaceutical Sciences, 2008, 23(6) |
| |
| Authors: | LU Jia ZHANG Su-juan QIAN Guang-sheng LI Zhang-wan FU Chun-mei |
| |
| Affiliation: | LU Jia,ZHANG Su-juan,QIAN Guang-sheng,LI Zhang-wan,FU Chun-mei(West China School of Pharmacy,Sichuan University,Chengdu 610041,China) |
| |
| Abstract: | OBJECTIVE To develop a subcritical water extraction (SWE) method to extract 4 alkaloids from Coptis chinensis Franch.METHODS The effect of pressure,temperature,extraction time and the solvent / sample ratio on the yields were investigated. Compared with the conventional organic solvent extraction method,the SWE method showed shorter handling time and lower solvent consumption.RESULTS The optimized SWE conditions for 4 alkaloids were that milled Coptis chinensis Franch was extracted twice at the solvent/samp... |
| |
| Keywords: | Subcritical water extraction Coptis chinensis Franch Alkaloids |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
