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鳞状细胞癌抗原与肝细胞癌的关系
引用本文:吴晓霞,黄智铭. 鳞状细胞癌抗原与肝细胞癌的关系[J]. 国际消化病杂志, 2008, 28(1): 66-68
作者姓名:吴晓霞  黄智铭
作者单位:温州医学院附属第一医院消化内科,325000
摘    要:鳞状细胞癌抗原(SCC-Ag)是一种肿瘤相关蛋白,SCC-Ag可能通过抑制肿瘤细胞凋亡和免疫细胞向肿瘤位置迁移参与恶性生物学过程。在肝细胞癌(HCC)组织,SCC-Ag的表达水平明显高于肝硬化组织和正常肝组织,HCC患者血清SCC-Ag水平亦明显高于肝硬化患者及正常人,SCC-Ag有可能成为新的肝细胞癌标志物。

关 键 词:鳞状细胞癌抗原  肝细胞癌  肿瘤标志物
修稿时间:2007-01-24

Relation of squamous cell carcinoma antigen and hepatocellular carcinoma
WU Xiao-xia,HUANG Zhi-ming. Relation of squamous cell carcinoma antigen and hepatocellular carcinoma[J]. International Journal of Digestive Disease, 2008, 28(1): 66-68
Authors:WU Xiao-xia  HUANG Zhi-ming
Abstract:Squamous cell carcinoma antigen(SCC-Ag)is a tumor associated protein.SCC-Ag probably participates in the malignant biologic behavior by inhibiting apoptosis of the tumor cells and migration of immune cells to the tumor site. The expression of SCC-Ag is much stronger in tumorous tissues of hepatocellular carcinoma(HCC) than in cirrhotic tissues and normal liver tissues.Moreover,the serum level of SCC-Ag is significantly higher in HCC samples than in cirrhotic and healthy samples.SCC-Ag may become a new tumor marker of HCC.
Keywords:Squamous cell carcinoma antigen  Hepatocellular carcinoma  Tumor marker
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