氨溴索雾化吸入治疗新生儿肺炎的疗效观察

目的探讨氨溴索雾化吸入对新生儿肺炎的疗效。方法选择我院诊断为新生儿肺炎的患儿144例，随机分为治疗组和对照组，对照组给予常规治疗，治疗组在常规治疗基础上加用氨溴索雾化吸入。比较两组治疗前后体温、呼吸频率、心率、总有效率和不良反应发生率。结果与治疗前比较，两组T、RR和HR明显降低，差异有统计学意义，P〈0．05；与对照组比较，治疗组RR和HR明显降低，差异有统计学意义（P〈0．05）。治疗组总有效率明显高于对照组，差异有统计学意义（P〈0．05）。两组均无特殊不良反应发生。结论氨溴索雾化吸入治疗新生儿肺炎安全、有效。

Efficiency and safety of ambroxol nebulization on infant pneumonia

Objective To investigate the efficacy and safety of ambroxol nebulization in the treatment of infant pneumonia. Methods A total of 152 infants with pneumonia were randomized into 2 groups, the control group received regular treatment, while the trail group received regular treatment plus ambroxo] nebulization. Temperature, respiratory rate, heart rate were analyzed before and after treatment for 72h. The total effective rate and side effeet were measured. Results After treatment for 72h, temperature, respiratory rate, heart rate were significantly decreased compared to baseline （P〈0.05）. The total effective rate was significant higher in the trial group than that in the control group （80.6% vs 65.3%, P〈0.05）. No serious side effects was observed in both groups. Conclusion Ambroxol nebulization is effective and safe in treatment of infant pneumonia.