绢毛蔷薇果实的化学成分

目的：研究绢毛蔷薇果实的化学成分。方法：将醇提取物用H₂O溶解,EtOAc萃取,经柱色谱分离纯化,通过波谱分析并结合化学转化鉴定化合物。结果：从该植物果实中分离、鉴定了6个化合物：euscaphic acid 3,4-monoacetonide (1), euscaphic acid (2), 4-O-β-D-吡喃葡糖基没食子酸甲酯(3),槲皮素(4),齐墩果酸(5),豆甾醇(6)。结论：1是新化合物,3为首次从植物中分离得到。

CHEMICAL CONSTITUENTS FROM FRUITS OF ROSA SERICEA

AIM: To investigate the chemical constituents of Rosa sericea Lindl. METHODS: The ethanol extract of the raw material was suspened in H2O and then exracted with EtOAc. The aqueous layer was chromatographed on a polyamide column with 95% EtOH successively. Then, each part was chromatographed repeatedly on silica gel column and the structures were identified by spectra and chemical methods. RESULTS: 6 compounds have been isolated and identified. CONCLUSION: The structures of the compounds were elucidated as euscaphic acid 3,4monoacetonide ( 1 ), euscaphic acid ( 2Z ), 4ODglucopyranosyl methyl gallate ( 3 ), quercetin ( 4 ), oleanolic acid ( 5 ) and stigmasterol ( 6Z ). Compound 1 is a new compound and the structure was affirmed by chemical transformations. Compound 3 was not reported before in plants and the structure was elucidated by 2DNMR.