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陕西地区无偿献血者Wra抗原分布多态性及其抗体频率调查——附临床抗-Wra鉴定2例
引用本文:褚晓月,左琴琴,毛娟,吴大洲,张薇薇,王红,张良子,徐华. 陕西地区无偿献血者Wra抗原分布多态性及其抗体频率调查——附临床抗-Wra鉴定2例[J]. 中国输血杂志, 2021, 0(1): 52-54
作者姓名:褚晓月  左琴琴  毛娟  吴大洲  张薇薇  王红  张良子  徐华
作者单位:1.陕西省血液中心
基金项目:2020年西安市科技计划项目(20YXYJ0009-6);西安市卫生健康委员会科研项目(2020yb47)。
摘    要:
目的 对陕西地区无偿献血者中Wra抗原频率及抗-Wra频率进行筛查.方法 使用血清学试验进行Wra抗原及抗-Wra频率的筛查以及血型、抗体鉴定;使用基因检测方法 进行确认.结果 筛查得出陕西地区7490名无偿献血者中Wra抗原检出率为0.013%(1/7 490);729名无偿献血者中抗-Wra的检出频率为0.823%...

关 键 词:抗-Wra  Wra抗原  基因分型  抗原多态性

Antigen profile and antibody frequency of Wr~a in voluntary blood donors in Shaanxi province,containing 2 clinical cases of anti-Wr~a identification
CHU Xiaoyue,ZUO Qinqin,MAO Juan,WU Dazhou,ZHANG Weiwei,WANG Hong,ZHANG Liangzi,XU Hua. Antigen profile and antibody frequency of Wr~a in voluntary blood donors in Shaanxi province,containing 2 clinical cases of anti-Wr~a identification[J]. Chinese Journal of Blood Transfusion, 2021, 0(1): 52-54
Authors:CHU Xiaoyue  ZUO Qinqin  MAO Juan  WU Dazhou  ZHANG Weiwei  WANG Hong  ZHANG Liangzi  XU Hua
Abstract:
Objective To understand the antigen profile and antibody frequency of Wr~a in voluntary blood donors in Shaanxi province. Methods Wr~a antigen and antibody screening as well as blood group typing and antibody identification were performed by serological tests and confirmed by genetic testing. Results The incidence of Wr~a antigen in 7 490 voluntary blood donors was 0.013%(1/7 490),and the frequency of anti-Wr~a in 729 voluntary blood donors was 0.823%(6/729).Conclusion This study explored the polymorphism of Wr~a antigen and antibodies in blood donors,which is informative in the risk assessment of blood transfusion and the screening and identification of respective antibodies.
Keywords:anti-Wr~a  Wr~a antigen  genotyping  antigen polymorphism
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