类似NEC表现的新生儿过敏性肠炎1例并文献复习

目的 研究新生儿过敏性肠炎临床表现,并与新生儿坏死性小肠结肠炎(NEC)鉴别,提高其诊治水平。方法 回顾性分析1例类似NEC表现的新生儿过敏性肠炎患儿临床资料,复习相关文献。结果 患儿为44 d女婴,生后4 d开始完全人工喂养后出现腹胀、呕吐、血便等症状,腹部影像学呈NEC表现,禁食后临床征象缓解,并反复发生。进一步行食源性过敏原测定示牛奶蛋白过敏。经抗感染并换用氨基酸配方奶喂养后所有症状消失。结论 新生儿过敏性肠炎可呈NEC表现,临床上需注意鉴别。

A case report on neonatal allergic colitis with similar symptoms to NEC and literature review

Objective To analyze clinical manifestations of neonatal allergic colitis,in order to improve the diagnosis and treatment compared with neonatal necrotizing enterocolitis (NEC). Methods Clinical data of a case with neonatal allergic colitis mimicking NEC was retrospectively analyzed and relevant studies were reviewed. Results A 44-day-old infant developed abdominal distension,vomiting,bloody stool over and over again since totally artificial feeding at 4 days of age with abdominal radiological findings similar with NEC,and clinical symptoms relieved after fasting.Further foodborne allergens test showed cow's milk protein allergy.All symptoms disappeared after anti-infection and amino acid-based formula (AAF) feeding. Conclusions Neonatal allergic colitis may show similar symptoms with NEC,so clinical staff should pay attention to indentify different diagnosis.