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复元活血汤抗炎镇痛作用的实验研究
引用本文:祖丽红,王继文. 复元活血汤抗炎镇痛作用的实验研究[J]. 中医正骨, 2003, 15(9): 17-18
作者姓名:祖丽红  王继文
作者单位:河南省郑州市中医医院,450007
摘    要:为研究复元活血汤的抗炎、镇痛作用,进行了药效学研究。结果显示,复元活血汤对醋酸引起的小鼠腹腔毛细血管通透性增加、角叉菜胶所致的大鼠足跖肿胀、二甲苯所致的小鼠耳肿胀均有显著的抑制作用;能显著降低小鼠腹腔注射醋酸引起的扭体反应次数,明显提高小鼠热板法的痛阈值,说明该药有较强的抗炎、镇痛作用。

关 键 词:复元活血汤 药效学 抗炎 镇痛 药物作用 动物实验研究 大鼠 小鼠
文章编号:1001-6015(2003)09-0017-02
修稿时间:2003-02-12

AN EXPERIMENTSL STUDY ON THE EFFECT OF “FUYUAN HUOXUE TANG”ON ANTI-INFLAMMATION AND ANALGESIA
Zu Lihong and Wang Jiwen TCM Hospital of Zhengzhou City,Zhengzhou. AN EXPERIMENTSL STUDY ON THE EFFECT OF “FUYUAN HUOXUE TANG”ON ANTI-INFLAMMATION AND ANALGESIA[J]. The Journal of Traditional Chinese Orthopedics and Traumatology, 2003, 15(9): 17-18
Authors:Zu Lihong  Wang Jiwen TCM Hospital of Zhengzhou City  Zhengzhou
Affiliation:Zu Lihong and Wang Jiwen TCM Hospital of Zhengzhou City,Zhengzhou 450007
Abstract:The anti-inflammatory and analgesic effect of "FUYUAN HUOXUE TANG""(FHT, a TCD decoction for restoring the vital energy and activating the blood circulation) was explored through pharmacodynamics studies. The results showed that FHT could significantly inhibit the acetic-acid-induced increase of mouse abdominal capillary permeability, carrageenin-induced rat planta edema and xylol-induced mouse ear edema, reduce the times of acetic-acid-induced mouse body twisting and improve the pain threshold of mouse hot plate method, suggesting that the drug has a strong anti-inflammatory and analgesic effect.
Keywords:FUYUAN HUOXUE TANG"  /pharmacodynamics, anti-inflammation/drug action, analgesia/drug action, experimental study, animal, mouse, rat,
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