Role of dyslipidemia in ischemic stroke patients treated in the telestroke network |
| |
| Institution: | 1. Department of Gastroenterology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland;2. Department of Radiology, Medical University of Bialystok, Bialystok, Poland;3. Department of Infectious Diseases and Hepatology, Medical University of Bialystok, Bialystok, Poland;1. Immunology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;2. Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran;1. Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran;2. Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran;3. Institute of Population Health Sciences, Barts and the London School of Medicine, Queen Mary University of London, United Kingdom;4. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran;1. Department of Pneumonology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland;2. Department of Respiratory Medicine, Allergology and Pulmonary Oncology, Poznan University of Medical Sciences, Poznan, Poland;3. Department of Epidemiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland;4. Department of Cardiac Anaesthesia and Intensive Care, Silesian Centre for Heart Diseases in Zabrze, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland;5. Faculty of Science and Technology, University of Silesia in Katowice, 75 Pu?ku Piechoty 1A, 41-500, Chorzów, Poland;6. Department of Swimming and Water Rescue, Institute of Sport Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland;7. Department of Anaesthesiology and Intensive Care, Medical University of Silesia, Katowice, Poland;1. Department of Fundamentals of Nursing, Faculty of Medical Science, Medical University of Warsaw, Warsaw, Poland;2. Department of Prevention of Environmental Hazards and Allergology, Faculty of Medical Science, Medical University of Warsaw, Warsaw, Poland;3. Institute of Information Technology, Warsaw University of Life Sciences, Warsaw, Poland;4. Department of Parasitology, Institute of Zoology, Faculty of Biology, University of Warsaw, Warsaw, Poland;5. National Institute of Public Health, Warsaw, Poland |
| |
| Abstract: | PurposeThe relationship between the telestroke technology and clinical risk factors in a dysplipidemic ischemic stroke population and neurologic outcomes is not fully understood. This issue was investigated in this study.Patients and methodsWe analyzed retrospective data collected from a regional stroke registry to identify demographic and clinical risk factors in patients with improving (NIHSS ?≤ ?7) or worsening (NIHSS ?> ?7) neurologic outcome in dyslipidemic ischemic stroke population. We used logistic multivariate models to identify independent predictors of improving or worsening outcome based on dyslipidemia disease status in ischemic stroke patients.ResultsIn the adjusted analysis for dyslipidemic ischemic stroke population, cholesterol reducer use (odd ratio; OR] ?= ?0.393, 95% confidence interval CI], 0.176–0.879, P ?= ?0.023) and direct admission (OR ?= ?0.435, 95% CI, 0.199–0.953, P ?= ?0.037) were more likely to be associated with neurologic improvement and no clinical or demographic factors were associated with poor neurologic outcome in dyslipidemic ischemic stroke patients treated in the telestroke network.For the ischemic stroke population without dyslipidemia, increasing age (OR ?= ?1.070, 95% CI, 1.031–1.109, P ?< ?0.001), coronary artery disease (OR ?= ?3.633, 95% CI, 1.307–10.099, P ?= ?0.013), history of drug or alcohol abuse (OR ?= ?6.548, 95% CI, 1.106–38.777, P ?= ?0.038), and improvement in ambulatory outcome (OR ?= ?2.880, 95% CI, 1.183–7.010, P ?= ?0.020) were associated with worsening neurological functions, while being Caucasian (OR ?= ?0.294, 95% CI, 0.098–0.882, P ?= ?0.029) was associated with improving neurologic functions.ConclusionDemographic and clinical risk factors among the dysplipidemic ischemic stroke population in the telestroke network were not associated with worsening neurologic functions. |
| |
| Keywords: | Dyslipidemia Stroke Telestroke Neurologic outcome NIHSS score |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
